All GLG News Analyses Filed Under: Orthopaedics
Analyses are solely the work of the authors and have not been edited or endorsed by GLG.
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Why not study it for osteoporosis?
June 11, 2007
Emisphere Announces Initiation Of Phase III Clinical Program Of Oral Calcitonin For The Treatment Of Osteoarthritis | www.medicalnewstoday.com
There has been no oral calcitonin formulation on the market as adequate delivery has been an issue. The use of intranasal for osteoporosis, is at best, a poor substitute for other agents on the market. It is interesting that there is no study on its use for osteoporosis. It is unclear why it should work on cartilage and not bone.
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Vertigraft VG2 is not likely to make an appreciable impact on DePuy Spine performance
June 1, 2007
Depuy Spine Introduces New Vertigraft® VG2® TLIF Allograft - Unique Construction Facilitates Bone Growth, Streamlined Insertion Technique | www.medicalnewstoday.com
The introduction of VG2 Vertigraft is not likely to make a significant contribution to the performance of DePuy Spine. This product offers little significant advantage over other currently existing products. While the TLIF procedure has been widely accepted as a useful technique in minimally-invasive spine surgery, this product does not offer a significant variation or improvement over competing products designed for TLIF procedures.
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globus adds to an already comprehensive product line
May 31, 2007
Globus Medical Introduces MARS(TM) Minimally Invasive Retractor System | www.medicalnewstoday.com
The introduction of this retractor system will enhance the position of Globus in the arena of minimally-invasive spine surgery. The retractor system is customizable, and addresses several of the shortcomings of other systems on the market.
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May 28, 2007
Learning curve may be longer than thought for placing hip resurfacing components | www.orthosupersite.com
This study purports that a greater volume of patients is needed to become proficient and accurate in placing hip resurfacing arthroplasty components; in this procedure patient selection is paramount. Achieving a case volume as listed in the article becomes difficult and performing resurfacing arthroplasties during a fellowship would greatly aid the surgeon in his ability to place components in his practice.
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May 28, 2007
Emisphere Announces Initiation Of Phase III Clinical Program Of Oral Calcitonin For The Treatment Of Osteoarthritis | www.medicalnewstoday.com
The risks, in monetary terms, are huge. But so are the rewards.
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May 23, 2007
FDA Approves Lovenox(R) (enoxaparin Sodium Injection) For The Most Severe Type Of Heart Attack | www.medicalnewstoday.com
Lovenox is clearly superior to unfractionated heparin when we look at global costs in the use of anticoagulation. This approval by the FDA gives it one more indication, and allows for simpler anticoagulation treatment.
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May 14, 2007
Protelos®: First Osteoporosis Treatment To Show Long-Term, Sustained Efficacy And Quality Of Life Improvement | www.medicalnewstoday.com
With the ability to prevent resorption and promote strong bone formation, this is a unique product. It will clearly assume a major role in th market if administration is easy and the side effect profile is minimal.
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Pfizer’s Lyrica: On Its way to An Approved Treatment for Fibromyalgia?
May 9, 2007
Pfizer’s Lyrica cuts fibromyalgia pain in study | www.reuters.com
While fibromyalgia is not well understood and sometimes conceived of as having psychosomatic contributions, it is estimated to affect up to 2% of the population and still has no FDA approved medication treatments for it.
Previous data on pregabalin (Lyrica; from Pfizer), a novel alpha-2 ligand, suggests it may help reduce pain and fatigue and improve sleep associated with fibromyalgia (in a 2005 randomized controlled trial). Lyrica is approved for treatment of diabetic peripheral neuropathy, post-herpetic neuralgia, and adjunctive treatment for partial onset seizures.
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April 22, 2007
Osteologix Completes Enrollment In Clinical Trial Of Investigational Drug For Osteoporosis | www.medicalnewstoday.com
Based on available data, there is no reason to think this will be a blockbuster.
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Wright Medical Group, Inc. Carolina (TM) Jones Fracture System for Foot & Ankle Surgery
March 29, 2007
Wright Medical Group, Inc. Launches the CAROLINA(TM) Jones Fracture System for Foot and Ankle Surgery | salesandmarketingnetwork.com
Jones fractures are traditionally difficult to manage. Wright Medical has a good range of sizes and lengths of screws. Because of the sizes, style, and lengths of this screws there may be other foot and ankle applications in the future. The percutaneous application will reduce make the risk of complications to the patient and potentially be easier and faster for the surgeon.
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