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All GLG News Analyses Filed Under: Orthopaedics

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Posted June 4, 2008
CMS ANNOUNCES DEMONSTRATION TO ENCOURAGE GREATER COLLABORATION AND IMPROVE QUALITY USING BUNDLED HOSPITAL PAYMENTS
Analysis of: CMS ANNOUNCES DEMONSTRATION TO ENCOURAGE GREATER COLLABORATION AND IMPROVE QUALITY USING BUNDLED HOSPITAL PAYMENTS | www.cms.hhs.gov
Author: GLG Member Program Contributor
CMS has the objective of keeping their costs down, increasing quality, protecting the Stark laws against physician referrals, and guarding against beneficiaries being enticed to receive more services than necessary.  CMS threw all these objectives into the ACE demonstration project.  The problems...
Posted May 27, 2008
That Must Be Bob. I Hear His New Hip Squeaking
Analysis of: That Must Be Bob. I Hear His New Hip Squeaking | www.nytimes.com
Author: GLG Member Program Contributor
The implant market is very competitive with surgeons being aggresive as early adopters to try to get a competitive edge and market themselves as using state of the art implants. This is pushed by the implant makers and often offer cooperative advertising....
Posted May 23, 2008
That Must Be Bob. I Hear His New Hip Squeaking
Analysis of: That Must Be Bob. I Hear His New Hip Squeaking | www.nytimes.com
Author: GLG Member Program Contributor
Ceramic hips, advertized as longer lasting and therefore better, actually have a shorter life if revised for stripe wear and making noise. Some surgeons felt that they should offer this type of surgery because patients were demanding it.
Posted February 11, 2008
This acqusition, and others, represent a significant upgrade of Alphatec's portfolio
Analysis of: Alphatec Holdings, Inc. Acquires An Exclusive Worldwide License for Innovative Dynamic Anterior Cervical Plate Technology | www.healthpointcapital.com
Author: Wayel Kaakaji, Chief Executive Officer and Medical Director Spinal and Neurosurgical Institute
Alphatec product line will expand and increase their market share The cervical plate from Progressive is much more promising than the Trestle plate developed by Alphatec, and should increase sales and improve the cervical implant portfolio
Posted January 25, 2008
Artificial Disc Versus Fusion: A Prospective, Randomized Study With 2-Year Follow-up on 99 Patients
Analysis of: Artificial Disc Versus Fusion: A Prospective, Randomized Study With 2-Year Follow-up on 99 Patients | www.medscape.com
Author: GLG Member Program Contributor
Outcomes in patients implanted with the artificial disc compare favorably with single level ACDF after 2 years.
Posted December 26, 2007
Medtronic loses litigation to DePuy over polyaxial Vertex screws, what is the significance?
Analysis of: U.S. Federal Court Issues Permanent Injunction Against Medtronic's Vertex And Vertex Max Screws | www.medicalnewstoday.com
Author: Wayel Kaakaji, Chief Executive Officer and Medical Director Spinal and Neurosurgical Institute
the use of Vertex polyaxial screws is only a minor part of the spinal implant protfolio at Medtronic (MDT:NYSE).  This should not affect the bottom line to any significant extent.
Posted December 14, 2007
Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair
Analysis of: Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair | www.pipelinereview.com
Author: GLG Member Program Contributor
Ever since Hyaluronans (HA) have been around to lubricate the the knee, arthroplasties have declined significantly for OA. This implies that finding the precise material necessary to keep the knee capsule full will prevent further degeneration of the joint and eventually the ultimate answer to treat...
Posted December 3, 2007
FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis
Analysis of: FORTEO(R) Increased Spine Bone Mineral Density in Patients with Glucocorticoid-Induced Osteoporosis | www.pipelinereview.com
Author: GLG Member Program Contributor
Though Forteo did  increase the BMD greater than alendronate, It did not decrease the amount of no-veterbral fractures which lead to increased morbidity and mortality.
Posted November 30, 2007
Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair
Analysis of: Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair | www.pipelinereview.com
Author: GLG Member Program Contributor
Stem cells plus HA provide a physiologically relevant combination that has real potential in tissue repair and regenerative medicine. But the press release goes further than warranted, in implying that Chondrogen addresses the OA market as a whole. The trial specifically evaluated the effects of the...
Posted November 30, 2007
Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair
Analysis of: Osiris Therapeutics Announces Positive One Year Data from Chondrogen Trial for Knee Repair | www.pipelinereview.com
Author: GLG Member Program Contributor
First of all, this is not a hypothesis generating study but a fishing expedition after an orthopedic procedure intervention. Maybe that's what happens when you let orthopedists loose with statistical analysis. Patients entered the study without any baseline osteoarthritis (OA) required...just a torn...
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