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All GLG News Analyses Filed Under: Ophthalmology

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Posted October 15, 2007
Maker Seeks to Restrict Cancer Drug Used on Eye
Analysis of: Maker Seeks to Restrict Cancer Drug Used on Eye | www.nytimes.com
Author: GLG Member Program Contributor
       Genentech has had first year revenues of $800 million from its drug Lucentis, which is used intravitreaaly to treat macular degeneration on label and some other conditions off label.   Although this amount of sales places Lucentis well within the blockbuster...
Posted October 15, 2007
Maker Seeks to Restrict Cancer Drug Used on Eye
Analysis of: Maker Seeks to Restrict Cancer Drug Used on Eye | www.nytimes.com
Author: GLG Member Program Contributor
-Avastin has been repackaged by some compounding pharmacies in place of Lucentis for an indication for which Avastin is not approved.  They are both Genentech drugs, but with Lucentis being much more expensive.  -This is a bit like grinding up amoxicillin tablets, making them into a suspension,...
Steve Rubinstein Posted October 12, 2007
Bad publicity for Genentech.
Analysis of: Maker Seeks to Restrict Cancer Drug Used on Eye | www.nytimes.com
Author: Steve Rubinstein, Optometrist Sound Shore Vision Care
How much should packaging of a drug cost?
Gary Barker Posted October 7, 2007
Neuroprotection is the Key in Glaucoma Treatment
Analysis of: Targeting amyloid- b in Glaucoma | www.pnas.org
Author: Gary Barker, Partner/Owner Eye Associates Of Winter Park
To delve further into the reasons for retinal ganglion cell death is critical for the future of glaucoma treatment. As the article discusses, there are reasons for retinal ganglion cell death other than high intraocular pressures.  Unfortunately, the only medical and surgical methods we have...
Posted September 21, 2007
Ophthalmic business: Alcon exceeds 70% stake in WaveLight
Analysis of: Ophthalmic business: Alcon exceeds 70% stake in WaveLight | www.osnsupersite.com
Author: GLG Member Program Contributor
Alcon holds more than 70% of Wavelights shares and its takeover of Wavelight has been approved by the German authorities. WHile wavelight produces some interesting intraocular lenses, it is clear that Alcons interest in Wavelight lies in its realiable and fast excimer laser system that can be used for...
Posted September 21, 2007
Targeting amyloid- b in Glaucoma
Analysis of: Targeting amyloid- b in Glaucoma | www.pnas.org
Author: GLG Member Program Contributor
New research indicating the presence of amyloid-beta protein in dying retinal cells  suggests a new direction in glaucoma research. Amyloid-beta is a protein found in Alzheimer's plaques. Using a rat model of glaucoma, the researchers found that the dying retinal cells showed accumulation of amyloid-beta....
Posted September 10, 2007
Lux Granted Fast Track Designation by FDA for LX211 for the Treatment of Uveitis
Analysis of: Lux Granted Fast Track Designation by FDA for LX211 for the Treatment of Uveitis | pharmalive.com
Author: GLG Member Program Contributor
LX211, calcineurin inhibitor and antiinflammatory drug, was granted Fast Track designation by the FDA. This move could expedite its approval for the management of non-infectious posterior, intermediate and panuveitis. In a field where there are few approved treatment modalities, this could be very big...
Posted September 7, 2007
Professional Boxer's Career In Jeopardy Because of Poor Contact Lens Hygiene
Analysis of: Aussie Boxing Champion Hospitalized Due To Eye Infection; Doubts About Career Prospects | www.allheadlinenews.com
Author: Darcy Ryan, Optometrist Hertzog Eye Associates
So how important is contact lens hygiene?  Extremely.  If you don't properly take care of your contact lenses, you risk vision loss. Would you change your bad habits if it were to cost you your professional career?  Most sane, competent people would emphatically say 'YES!'. ...
Steve Rubinstein Posted September 4, 2007
COMPLETE® MPS Easy Rub™ Formula....Whats the active ingredient?
Analysis of: Advanced Medical to Ship Solution | biz.yahoo.com
Author: Steve Rubinstein, Optometrist Sound Shore Vision Care
AMO has come out with a "new" product to be released in Sept 2007. But they have not announced what the key active ingredient is. The active ingredient(disinfectant) can determine where it stands compared to other products available on the market in the US. I list most of the various contact lens care...
Posted September 4, 2007
Advanced Medical to Ship Solution
Analysis of: Advanced Medical to Ship Solution | biz.yahoo.com
Author: GLG Member Program Contributor
How did AMO develop a novel contact lens solution so quickly? Is this really a brand new formula? How will AMO regain the confidence of eye care professionals and the public with regard to their contact lens related products?
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