All GLG News Analyses Filed Under: Oncology

Families will treat their loved ones with combinations of drugs rather than than seeking appropriate clinical trials.

Should the cost of a drug make a decision of an official authority more strict?

Geron's cancer vaccine targets telomerase which is active in growth of many cancers. Eraly clinical trials are ongoing in AML and vaccine may have role in melanoma, sarcomas, NHL and lung cancer. Main role of cancer vaccines is in minimal residual disaese or as maintenanence/consolidation therapy...

Not enough detail to understand the meaningfulness of any of the data reported.   Maybe a hint of activity? 

Vaccine targeting non infectious agents to control neoplasia.

Qt prolongation a real concern. Seek another molecule unless mechanism responsible. hERG presumably run and was falsely reassuring. 

     Medicare has decided to cut payments to hospital nuclear medicine departments for this valuable therapy for patients with low grade non Hodgkins lymphomas. The reimbursement will be less than the cost??? This will force patients to be treated instead with ultimately more expensive...

“On face value the data look very good,” said Buzdar, who voted with the slim (5-4) majority against the drug. In the study that was the basis of Genentech’s application, Avastin appeared to slow the progress of the disease. advanced breast cancer who had already tried other drugs. He said he’s never...

The FDA has rejected use of Avastin in metastatic breast cancer as I anticipated! http://biz.yahoo.com/ap/071205/genentech_avastin.html

Interesting spectrum of agents in development to supplement their already impressive lineup.