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All GLG News Analyses Filed Under: Infectious Disease

Articles with lock require a GLG News subscription
Posted April 14, 2008
Clinical Analysis of GSK's Rotarix important to success of vaccine
Analysis of: FDA Clears Glaxo Diarrhea - Virus Vaccine | www.nytimes.com
Author: GLG Member Program Contributor
The key to success of marketing Rotarix or similar Rotavirus vaccines is in the design of clinical trials and evaluation of criteria and results of past use of these vaccines in developing countries that have a high incidence of rotavirus diarrhea in infants.  Rotavirus vaccine use...
Posted April 14, 2008
Cubicin not tainted but delivery device.
Analysis of: Cubist Finds Its Antibiotic Cubicin Is Tainted | online.wsj.com
Author: GLG Member Program Contributor
            ReadyMED® is a infusion device used primarily in outpatient settings for administering antiobiotics in the home.  ReadyMED® requires little patient or caregiver training and works by gravity.  No IV poles or pumps...
Eric Gruff Posted April 14, 2008
Cubist's Antibiotic Cubicin is Tainted: A Mess Not of Their Doing? Maybe, Maybe Not.
Analysis of: Cubist Finds Its Antibiotic Cubicin Is Tainted | online.wsj.com
Author: Eric Gruff, Principal E4 Consulting
The news that Cubist's Cubicin has been contaminated with 2-mercaptobenzothiazole (MBT) has caused great concern for patients. It appears that the MBT has leeched out of the Cardinal Health ReadyMED drug pumps that are used for delivering Cubicin. Regardless of who is at fault, everyone involved (Cubist,...
Posted April 7, 2008
Let the Rotavirus battle begin!
Analysis of: FDA Clears Glaxo Diarrhea - Virus Vaccine | www.nytimes.com
Author: GLG Member Program Contributor
-Glaxo's Rotarix vaccine was approved last week for prevention of rotavirus infection in infants -Merck's product, Rotateq, on the market for 2 years in the US, already has an established pipeline to essentially all pediatric primary care providers -There are small differences between the 2 vaccines,...
Posted April 4, 2008
Herpes Labialis Medicaments
Analysis of: Medivir: Lipsovir Prevents Cold Sores - Phase III Clinical Trial Results First to Show Prevention by Early Treatment | pharmalive.com
Author: GLG Member Program Contributor
This article fails to explain how Lipsovir will prevent breakouts of new lesions.  They say that early use of the ointment in an episode will shorten the duration about 1 1/2 days but where is the evidence that it prevent new episodes?  Also there is a lot of viral resistance to acyclovir,...
Posted March 31, 2008
Impressive Opportunity Treatment for Prevention of Pandemic Flu
Analysis of: Study Finds Single Dose of Iomai Patch With Pandemic Flu Vaccine Achieves Protective Levels | www.pipelinereview.com
Author: GLG Member Program Contributor
This drug in the form of a patch will solve one problem of vaccination for the Pandemic Flu; that is the two-step process. It also may have impact on the autistic concerns associated with immunizations that are administered containing small amounts of mercury.
Posted March 31, 2008
Prevention is better than cure - Medivir's successful phase III clinical trial for Lipsovir(R)
Analysis of: Medivir: Lipsovir Prevents Cold Sores - Phase III Clinical Trial Results First to Show Prevention by Early Treatment | pharmalive.com
Author: GLG Member Program Contributor
The article published in the www.pharmalive.com is presenting a very useful information for preventing common illness, such as cold sores. The successful clinical outcome from phase III trial for Lipsovir is a progressive step for Medivir to develop preventative medicine. Particularly,  the combination...
Posted March 28, 2008
Will have a niche
Analysis of: Medivir: Lipsovir Prevents Cold Sores - Phase III Clinical Trial Results First to Show Prevention by Early Treatment | pharmalive.com
Author: GLG Member Program Contributor
Many patients wish to rid themselves of recurrent cold sores. If this cream really works, there will be a market for it.
Posted March 27, 2008
Drugs May Help - Studies With Patient Education Needed
Analysis of: XTL in $108 million licensing agreement for Hepatitis C program with Presidio | www.forbes.com
Author: GLG Member Program Contributor
This is a promising shift of money into licensing a drug may be a helpful tool to abate the symptoms. Patient education is an essential component in the treatment of this disease. In a clinical research study in 1999, the use of acupuncture, herbal medicine and patient education were the best...
Posted March 26, 2008
Impressive results in competitive environment
Analysis of: Ardea Biosciences Reports Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating up to 2.0 Log Reduction in Plasma Viral Load | www.pipelinereview.com
Author: GLG Member Program Contributor
Impressive 7 day antiviral effects Potential for QD naive and BD experienced approaches Potential for coformulations Revised formulation moving into next phase of testing No critical safety issues in volunteers or patients Metabolit may be anti-gout agent
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