All GLG News Analyses Filed Under: Infectious Disease

Peramavir's future still looks promising despite the failure of phase II trials to show statistical significance.  As described in the article, this may be mainly due to the fact that the injections may not have been administered properly because of the shorter needles.  Since, the post hoc...

The FDA recently approved the expanded use of FluMist, the only nasal spray influenza vaccine, in children 2 to 5 years of age. Each year in the U.S up to 60 million Americans get the flu according to the CDC. The U.S. CDC recommends all children aged 6 to 59 months be vaccinated against the flu. FluMist...

More candidates for Flumist have thus been identified. But the cost and insurance coverage issues remain, as does the fact that it is not approved for anyone with a significant health issue.

A shame that thjis promising drug did not reach statistical significance in the study.   

Release of a news regarding the co-administration of Rotarix(R), an oral candidate vaccine for infants to prevent rotavirus gastroenteritis, with routine vaccines for two and four months old immunization stage is definitely an interesting development. The result of the clinical trials indicating...

The news is very important for showing the effectiveness of this drug to reduce the suffering of TB patients, and also to prevent from further transmission to others. The disease is epidemic in the developing world, where a cry for medical treatment in evident. This news may appear as a relief for such...

* New class of antibiotic with activity against MRSA that has been used in the US to treat sepsis and severe infections. * As or more expensive than other drug regimens for the patient populations indicated. * Resistance to daptomycin has been reported in MRSA and enterococci. * Has a role, but generally...

* Some interesting in vitro data regarding cidal/killing activity of oritavancin, another peptide antibiotic in the same class as vancomycin. * No significant animal models to date. * One study has shown some toxic effects on eukaryotic cells in vitro. * Remains to be determined if this antibiotic...

Antimicrobial resistance is becoming more and more prevalent. If this agent holds up in clinical trails it will be a needed brekthrough.

- flumist will prove attractive to parents of young children, because   young children are the group most traumatized by injections