All GLG News Analyses Filed Under: Infectious Disease

The vaccine has shown superiority over the existing vaccine. Unless there are major side effects it should replace what we have.

This study, although an abstract has no statistical power. Even a quick overview reveals that the ß for this study is insufficient to make the (marginallY) "significant" results achieved newsworthy. I understand the importance of disseminating information but this article fails in that regard.

An encouraging development, however since the vaccine does not cover group B meningococcal disease, vigilance will be required among vaccinated individuals to insure that symptomatic individuals are not infected with group B meningococci.  The human bactericidal antibody response is considered...

Menveo appears to have some statistical advantages over the currently available product, Menactra (sanofi aventis.) Whether the higher antibody levels translate into better or more lasting protection remains to be seen. Given recent FDA action approving meningococcal vaccine for younger pediatric age...

Microbes have a remarkable ability to mutate to allow for their survival.  Biologics can introduce new means of treating invections, but are unlikely to overcome the ability of them to become resistant.  Several biological components have been studied by companies and claim lack of resistance....

Ricin is an extraordinarily potent toxin that is fatal because of its ability to inhibit protein synthesis and rapidly cause multisystem failure.  Because ricin can be prepared from castro beans, it has the potential to be used in terrorist attacks.  The present vaccine has the potential to...

Immunomodulation especially with antibodies is difficult.  Proteins are not as easily given and distributed through the body as low molecular weight compounds.  I believe that the first drug to be effective will pave the way for many others

The key to success of marketing Rotarix or similar Rotavirus vaccines is in the design of clinical trials and evaluation of criteria and results of past use of these vaccines in developing countries that have a high incidence of rotavirus diarrhea in infants.  Rotavirus vaccine use...

            ReadyMED® is a infusion device used primarily in outpatient settings for administering antiobiotics in the home.  ReadyMED® requires little patient or caregiver training and works by gravity.  No IV poles or pumps...

The news that Cubist's Cubicin has been contaminated with 2-mercaptobenzothiazole (MBT) has caused great concern for patients. It appears that the MBT has leeched out of the Cardinal Health ReadyMED drug pumps that are used for delivering Cubicin. Regardless of who is at fault, everyone involved (Cubist,...