All GLG News Analyses Filed Under: Cardiology

This new class of antihypertensive has not really gotten the press, that one would expect. It effects the renin system up front. However, just like ACE and ARB's it is not better in blacks. It's side effect profile is also very similar to existing ACE inhibitors. Whether it will be a better drug will...

Symbicort will be the second combination of a LABA/steroid  to come to the market. It's ability to provide rapid and long standing brochodilation, may make it a better product than Advair. However, the potential for overuse and subsequent adverse effects will also rise if not used properly.

How new is this formulation? The data suggest that it will help with ocular symptoms as well. This is what will make it unique. Nasal steroids usually do not do well with ocular symptoms. We will need more data.

Here is another example of how nosocomial problems arise. No bacteria were found in the vials of the multi-dose product. It is likely that better infection control methodology needs to be employed. The more hands, the worse of you are.

Still once a day, but now more useful for ocular allergies.

1. Atrial fibrillation ablation is one of the fastest growing procedural areas in cardiac electrophysiology. 2. There is a need to achieve a higher success rate than is currently being observe. 3. The majority of afib ablations are performed using radiofrequency energy. 4. Other ablation technologies...

This article summarizes phase III clinical data studying fluticasone furoate nasal spray. Fluticasone furoate nasal spray was more effective than placebo in controlling the nasal symptoms of perennial allergic rhinitis. Fluticasone furoate nasal spray was also more effective than placebo in controlling...

Percutaneous valves are being developed by CoreValve. Edwards-PVT, and other manufacturers as a less invasive option for valve replacement.These valves have been shown to be technically implantable, although they have significant morbidity and mortality.They have the short term potential to increase...

The Medtronic device for monitoring cardiac health was rejected by an FDA Advisory committee last week.  This was justified given the paucity of the data and lack of statistical significance.

1. The chronicle device is a stand alone hemodynamic monitor  that is implanted in a similar fashion as a pacemaker.  It includes a wire that is capable of measuring blood pressure in the lungs.  This pressure measurement may serve as a early warning of worsening heart...