All GLG News Analyses Filed Under: Cardiology

This drug will compliment Lotrel in the Hypertension market. Novartis will now have an Amlopidine-ACE and an Amlodipine-ARB combination. Which will be better is unclear as of yet, but the choice is now there.

Though a once-a-day amoxicillin is likely to lead to more compliance, giving a drug for a shorter period of time would be better. It will allow for a full course of therapy. The longer a drug needs to be taken the less likely it will be completed as patients will tend to stop therapy once they feel...

The main advantage of this formulation is being once a day, to improve compliance. The standard dose seems to be 775 mg/d for 7 days (compared to 500 tid for 10-days) which also could potentially decrease side effects with a lower dose and shorter duration.

We already have combination meds that include a CALCIUM CHANNEL BLOCKER and an ACE. Amlodipine is in one of these combination products. Combination therapy is the way to do to get patients to goal with a lower pill burden. Which combo of an ACE or an ARB  with Amlodipine will be better...

This is the second generic version of Fenofexadine(Allegra).  Its presence on the market should result in lower prices for this generic drug. It puts even greater pressure on Zyrtec and Clarinex to maintain market share.

Fexofenadine, a popular oral anti-histamine, is an attractive target, but the market for oral anti-histamines is very competitive. 

An NDA for Regadenoson has been submitted this week. The compound has a few significant benefits over adenosine: 1- bolus vs. 4 minute drip 2- Fewer symptoms. The compound has been shown to lead to essentially identical stress images. The drug will be marketed by Astellas who will push hard to switch...

There are millions of VT patient all over the world. Quite a few of them have Defibrillators implanted. However because VT ablation is a complex procedure very few cases are attempted worldwide in comparison to the number of cases present. Newer technologies might change the scenario. Use of remote...

All individuals from 3rd world nations should be screened for communicable diseases upon entry to a developed nation. This may stem the tide of spread in that country. It does not affect the real issue of controlling disease where it originates.

Only good can come from this. Combination products are now the way to go in control of hypertension. The HOPE study has shown that Altace has evidence based positive outcomes. King Pharma can only benefit from this.