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All GLG News Analyses Filed Under: Cardiology

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Posted July 24, 2007
Takeda's TAK-491 for Treatment of Hypertension remains a hopeful.
Analysis of: Takeda's Investigational Compound TAK-491 for Treatment of Hypertension Enters into Phase 3 Clinical Stage in the U.S. and Europe | www.pipelinereview.com
Author: GLG Member Program Contributor
The claims made by Takeda are powerful, but only after one or more phase III clinical will the firm be able to affirm the claims.
Posted July 23, 2007
Another arrow in the quiver to treat OSA
Analysis of: Sleep apnea device may improve patient outcome | www.reuters.com
Author: GLG Member Program Contributor
The Reuters article presents a summary of a study conducted by reseachers at Johns Hopkin's Hospital and reported in the highly respected journal of the American Thoracic Society. The writer of the article confounds, as many writers do when writing about using continuous pressure to treat obstructive...
Posted July 20, 2007
Sleep Apnea device good for some not for others
Analysis of: Sleep apnea device may improve patient outcome | www.reuters.com
Author: GLG Member Program Contributor
Who would gain from a device that requires once to carry around a bulky oxygen tank vs using simple air?
Posted July 19, 2007
Tremendous savings in time and Efficiency for Device Clinics and Patients
Analysis of: Medtronic Launches First Wireless Devices In Japan -Concerto® CRT-D And Virtuoso® ICD Now Available For Japanese Patients | www.medicalnewstoday.com
Author: GLG Member Program Contributor
1. Shorter office Visits for device checks 2. Increases Device clinic efficiency and throughput 3. Speeds implant procedure and lowers the chance of contamination. 4. Provides ATP during charging, which allows a painless attempt at arrhythmia conversion, without delaying a shock if the painless method...
Posted July 18, 2007
FLAP over asthma.
Analysis of: Amira Pharmaceuticals Starts First Clinical Trial of Lead Compound With Potential in Asthma and Cardiovascular Disease | www.pipelinereview.com
Author: GLG Member Program Contributor
To answer the client question: yes.  The question then is: to what degree?
Posted July 18, 2007
Confusing Report of Alternative to CPAP
Analysis of: Sleep apnea device may improve patient outcome | www.reuters.com
Author: GLG Member Program Contributor
Are there misprints in the article regarding the use of "warm humidified air" as an alternative to CPAP? In the article there are repeated references to "oxygen supplied by nasal tube" and "oxygen therapy using a single nasal tube". What was provided the patient - oxygen or air?
Posted July 18, 2007
A Promising New Therapy For a Disease on the Increase
Analysis of: New Method Could Pull the Mask Off Apnea Treatment | www.medpagetoday.com
Author: GLG Member Program Contributor
- the standard of care for obstructive sleep apnea is a CPAP mask,   which most patients hate - this new therapy uses a much more comfortable nasal cannula   but has only been studied in MILD cases of sleep apnea - the incidence of sleep apnea is expected to increase sharply
Posted July 12, 2007
Simplifying DVT prophylaxis
Analysis of: Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery | www.pipelinereview.com
Author: GLG Member Program Contributor
One of the major issues with treatment and prophylaxsis of DVT and PE is the need to use an initial product that requires either IV administration {heparin] or adjusted dose LMWH via injection. Having an oral product will allow easier administration and decrease hospitalization.It will also preclude...
Posted July 12, 2007
Chantix is a concept now, at Phase III all the investors will want to be in the know.
Analysis of: Anti-smoking drug Chantix works for alcohol too | www.news-medical.net
Author: GLG Member Program Contributor
These clinical studies are in rats, pigs might be a better model in most cases for humans, but in either case it is not know to be tested on one person. When human data is generated then there may be important progress.
Posted July 11, 2007
Self expanding stents: the third generation
Analysis of: Scrutiny of Stent Problems Turns to Doctors | online.wsj.com
Author: GLG Member Program Contributor
The next generation of coronary artery stents The current proglems that have plaque the stents availble today appear to center on the individual physician and the inflation pressure he uses to deploy the stent.  Soon to be published data from the pathology group at the University of Minnisota appear...
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