All GLG News Analyses Filed Under: Cardiology

Clobutinol, a centrally acting cough suppressant (meaning that it works at the level of the brain to suppress the cough reflex), was voluntarily withdrawn from the marketplace by B.I., and now officially banned by a German regulatory agency, following reports that the drug may precipitate life-threatening...

The MHRA -- the UK's version of the FDA -- is pondering action to restrict the volume of sales of pseudoephedrine and ephedrine, two OTC nasal decongestant products with amphetamine properties. The motivation behind the recommendation is a hope to curtail the rampant black market production of...

St. Jude Medical has greatly modified their Angioseal closure device over the years to provide a device that is both efficacious and user friendly.  One of the difficulty with previous versions was the multiple steps, but with the STS platform, they have created a device that provides complete...

- we are in the midst of a worldwide cystal methedrine abuse epidemic - crystal meth can be easily made using ephedrine or pseudephedrine -   commonly used decongestants - in response to this epidemic the U.S. has already passed similar laws   to what has just been passed in the UK - expect...

The repositioning of the hole, also present with the VIP version is a mild improvement to decrease sheath manipulation. Otherwise the device has not changed much in the past few years. While a very good device in general, its primary limitaions listed below still remain. 1. not allowing re-access...

A "best-seller" anti-H1 in Europe finally arrives to USA

Zyrtec will soon be available over the counter and this new product will attempt to keep the antihistamine market share for Sanofi-Aventis - although Zyrtec is presently manufactured by Pfizer.  The antihistamine market is quite large and the OTC versus prescription situation is making this problematic...

The key implications remain 1)Safety 2)Efficacy 3)Cost 4)Complications e)Outcome analysis

The frequency of proton pump inhibitors (PPI) prescriptions make FDA review an important step in the long-term assessments of their risk-benefit profile.  It is important to recognize that the FDA did not change the prescribing indications or even issue a warning to physicians about the use of...

   Zyrtec (cetirizine) is a second generation nonsedating antihistamine that has enjoyed wide popularity.  Zyrtec will become available generically in late 2007 and the generic form is expected to be significantly cheaper.  To virtually extend the patent, the manufacturer is...