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All GLG News Analyses Filed Under: Business of Medicine

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Posted April 28, 2008
GlaxoSmithKline to acquire Sirtris Pharmaceuticals, a world leader in 'Sirtuin' research and development
Analysis of: GlaxoSmithKline to acquire Sirtris Pharmaceuticals, a world leader in 'Sirtuin' research and development | www.pipelinereview.com
Author: GLG Member Program Contributor
Situins are enzymes that regulate predetermined cell death, activity in muscle and fat cells as well as energy expenditure. There are several classes of these enzymes (SIRT 1 through 7). The technology is promising in that it promises to regulate some of the causes of diabetes and obesity rather than...
Posted April 28, 2008
The Price of Excess--Identifying Waste in Healthcare Spending
Analysis of: The Price of Excess--Identifying Waste in Healthcare Spending | www.pwc.com
Author: GLG Member Program Contributor
For the first time a major comprehensive authoritative national study (by PricewaterhouseCoopers, LLP) has concluded that over one half of the nation's $2.2 trillion in annual health spending (fully $1.2 trillion) is wasted.  Other studies have put this percentage in the 25 to 40% range. ...
Louis Sanfilippo Posted April 28, 2008
Glaxo Decision Moves Drug Development Forward Again
Analysis of: Federal Court Sides With GlaxoSmithKline, Strikes Down Rules Issued by Patent Office | biz.yahoo.com
Author: Louis Sanfilippo, President LCS Group, LLC
The USPTO’s proposed rule changes, struck down in this important Glaxo federal court decision, would have added significant burdens to pharmaceutical companies in developing their IP portfolios and ultimately their drug treatments.   The proposed changes were seemingly motivated to make the...
Mark Tapsak Posted April 24, 2008
Industry leaders need to work with the US Patent and Trademark office to keep US patents strong
Analysis of: Federal Court Sides With GlaxoSmithKline, Strikes Down Rules Issued by Patent Office | biz.yahoo.com
Author: Mark Tapsak, Assistant Professor Bloomsburg University of Pennsylvania
The USPTO is facing an epidemic amount of frivolous patents.  This degrades their ability to review strong and potentially important patents in a timely manner.  Although this particular change was struck down in Federal court, industry leaders need to work with the USPTO in order...
Posted April 23, 2008
U.S. Identifies Tainted Heparin in 11 Countries
Analysis of: U.S. Identifies Tainted Heparin in 11 Countries | www.nytimes.com
Author: GLG Member Program Contributor
The counterfeiting of drugs -- which encompasses not only products that are completely fake, but also those that have been tampered with, contaminated, diluted, repackaged or mislabelled in a way that misrepresents the contents, dosage, origin or expiration date -- is a huge and growing problem. ...
Posted April 22, 2008
Reports: Data on Vioxx was misused
Analysis of: Reports: Data on Vioxx was misused | www.usatoday.com
Author: GLG Member Program Contributor
Merck continues to have problems as a result of Vioxx.  It recently came out that the research studies which had been allegedly authored by independent medical scientists were actually ghostwritten by individuals paid by Merck. Many physicians have a poor opinion of industry sponsored research...
Posted April 22, 2008
Roche fully acquires privately-owned biotech company Piramed
Analysis of: Roche fully acquires privately-owned biotech company Piramed | www.pipelinereview.com
Author: GLG Member Program Contributor
PI 3-kinases are enzymes that play a role in the functioning of cells and their response to stimuli. In essence, these enzymes form portions of the ‘production line’ in cells. Turning up the tempo in this 'production line' is though to play a role in cancer growth and uncontrolled inflammation...
Posted April 21, 2008
Debiopharm and Airmid Sign Option and License Agreement
Analysis of: Debiopharm and Airmid Sign Option and License Agreement | www.pipelinereview.com
Author: GLG Member Program Contributor
Potassium channels are ‘pores’ in the membrane surrounding cells that modulate the flow of potassium (also called ‘K+’). This modulation is one of the basic interactions of life in all living cells. The scientific community is still learning the ramification of the modulation of these channels.
Richard Baland Posted April 21, 2008
What can Hospitals do about their Spending and Borrowing in 2008?
Analysis of: University Hospitals in Cleveland makes aggressive refinancing move | blog.cleveland.com
Author: Richard Baland, Chief Financial Officer & Chief Compliance Officer Richardson Medical Center
Increasing interest rates and debt service, a Decrease in available cash, a Migration to more fixed rate borrowing and appeals to state governments for assistance, a delay in physical plant additions/upgrades
Posted April 21, 2008
Reports: Data on Vioxx was misused
Analysis of: Reports: Data on Vioxx was misused | www.usatoday.com
Author: GLG Member Program Contributor
The more we learn the more likely it is that we cannot trust big pharma or the scientists who get grants to do research for them. The FDA really needs to do a better job to protect the public!
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