Study Group: Sleep Physicians (US)(?)

Eicosanoids appear promising in the treatment of such airways diseases as COPD and asthma, which affect millions worldwide.  Any alternative to current anti-inflammatory therapy, which consists almost entirely of forms of corticosteroids, would almost certainly be welcomed and adopted in widespread...

Cephalosporins have been standard therapy for pneumonia for many years, but to date this class of drug has been ineffective against MRSA.  Ceftobiprole appears to represent a breakthrough in this regard.  I would expect the drug to be well tolerated and, for the most part, to cause few major...

Though the potential international market for eszopiclone is large, interest in the product among sleep specialists in the US has leveled off.  Its success internationally may well depend more on distancing the product from other agents such as the Ambien "family," a decidedly difficult task, and...

These data help strengthen the growing perception that oral agents in general, direct thrombin inhibitors in particular, and perhaps specifically dabigatran, represent the future of anticoagulation therapy.  Safety data are of paramount importance, given the prior failure of ximelagatran in this...

Phase I data are promising for prevention on VTE, a major worldwide health problem.  However, inhibition of factor VIII raises grave safey concerns, despite safety profile in this study.  Long duration of action and cost also will be important considerations (current drug costs for this indication can...