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Study Group: Multiple Sclerosis Neurologists (EU)(?)

Council Members in this Study Group: 102

This study group may include physicians, care providers, and researchers specializing in internal medicine, cardiology, oncology, dermatology, emergency medicine, family medicine, neurology, obstetrics-gynecology, psychiatry, radiology, nursing, optometry, genetics, and mental health. It may also include experts knowledgeable on diagnostic labs, disease management, medical devices, long term care, surgery centers, health management, pharma, and biotechnology, among others.

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I am not sure that 4-aminopyridine, a long known drug, will efectively improve walking. As important as the walking ability are other clinical features of MS, e.g. ataxia, dementia or bladder dysfunction. This should also be tested.

There is not much information of the drug ALS-02 in the paper. The term neuroprotection is defined not very well and describes a great number of different molecular mechanisms. The low number of patients will not allow implications for clinical efficacy.

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