Council Members in this Study Group: 91
This study group may include experts knowledgeable on topics such as automotive manufacturing and dealerships, after market distribution, alcoholic and non-alcoholic beverages, convenience stores, supermarkets, packaged goods manufacturing, department stores and discounters, jewelry and cosmetics, hotels and resorts, restaurants, casinos, and the travel industry, among others.
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Keith AllenDirector, Cardiothoracic Vascular Surgery Research
Mid America Heart & Lung Surgeons, PC![]()
Keith Allen, MD, is a Director of Cardiothoracic-Vascular Surgery Research at the Mid America Heart Institute in Kansas City, Missouri. He is board certified in Thoracic, Vascular, and General Surgery. Dr. Allen maintains an active clinical research department...
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Drug Eluting Stents:The Next Vioxx
December 14, 2006
Trading restenosis for Thrombosis? New questions about drug-eluding stents. | content.nejm.org
1. DES whether used on or off label will likely require life long anticoagulation with Plavix like drugs.
2. The incidence of late thrombosis is significant when anticoagulation is interrupted for events such as elective surgery.
3. Unlike restenosis following insertion of a bare metal stent which rarely results in death to the patient, late thrombosis following use of a DES results in a 50% mortality.
4. Hints of this problem were present during FDA presentations prior to DES approval which may lead to significant liability as this problem becomes more apparent.