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Study Group: Bosentan Prescribers for PAH (US)(?)

Council Members in this Study Group: 80

This study group may include physicians, care providers, and researchers specializing in internal medicine, cardiology, oncology, dermatology, emergency medicine, family medicine, neurology, obstetrics-gynecology, psychiatry, radiology, nursing, optometry, genetics, and mental health. It may also include experts knowledgeable on diagnostic labs, disease management, medical devices, long term care, surgery centers, health management, pharma, and biotechnology, among others.

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Leading Experts in this Study Group

Ray Coakley, MD, PHD
Ass. Professor in Medicine
University of North Carolina at Chapel Hill School of Medicine - CC

Ray Coakley, MD PhD, is a physician scientist / pulmonary & critical care specialist at the University of North Carolina, Chapel Hill. His clinical and research focus is on COPD, cystic fibrosis, lung transplantation and PAH. Specific research expertise includes airway epithelial ion/fluid transport...

Herbert Baraf, MD, FACP, FACR, Clinical Associate Professor of Medicine, UNIVERSITY OF MARYLANDHerbert Baraf, MD, FACP, FACR
Clinical Associate Professor of Medicine
UNIVERSITY OF MARYLAND

Herbert Baraf, MD, FACP, FACR, is the Managing Partner of Arthritis and Rheumatism Associates and the Medical Director of Center for Rheumatology and Bone Research in Maryland. He is also the Clinical Professor of Medicine at George Washington University Medical Center and Clinical Associate Professor...

Robert Aris, MD, Associate Professor of Medicine, University of North Carolina Chapel Hill - CCRobert Aris, MD
Associate Professor of Medicine
University of North Carolina Chapel Hill - CC

Robert Aris, MD, is an Associate Professor of Medicine at the University of North Carolina Chapel Hill. He is the Director of the Pulmonary Hypertension Program, the Lung Transplant Research Program and Inpatient Pulmonary Services. Dr. Aris has expertise in advanced lung diseases including cystic...

Warren Botnick, MD
President
PSS Clinical Research

Warren Botnick, MD, FCCP, DABSM, is a Partner at Pulmonary and Sleep Specialists in Decatur, Georgia, since March 2003. He is Director of Critical Care Unit and Chief of Medicine at DeKalb Medical Center, Medical Director of Southern Sleep Technologies, and Co-Director of two sleep disorders centers...

Robyn Barst, MD, Director, New York- Presbyterian/Columbia University Medical CenterRobyn Barst, MD
FormerDirector
New York- Presbyterian/Columbia University Medical Center

Robyn J Barst, MD is Professor Emeritus of Pediatrics (in Medicine) at the College of Physicians and Surgeons at Columbia University. She was Director of the New York-Presbyterian Pulmonary Hypertension Center 1982-2008. She is a Fellow of the American Academy of Pediatrics, American College of Cardiology,...

Victor Tapson, MD, Medical Director of Pulmonary Hypertension Center, Duke UniversityVictor Tapson, MD
Medical Director of Pulmonary Hypertension Center
Duke University

Victor Tapson, MD, is Professor of Medicine in the Division of Pulmonary and Critical Care at Duke University School of Medicine and the Medical Director of the Duke Pulmonary Hypertension Center. Dr. Tapson was Director for the Duke Lung Transplant Program for over 10 years and Director for the Center...

Kamal Mubarak, MD
Assistant Professor & Director
University of Florida

Kamal Mubarak, MD, is an Assistant Professor and Director of the Pulmonary Vascular Disease Program at University of Florida, Gainesville. Dr. Mubarak's clinical specialties include Internal Medicine, Critical Care Medicine, and Pulmonary Disease. He is involved in numerous clinical trials in treating...

Inder Anand, MD, FACC, FRCP, DPhil, Director of the Heart Failure Program, Minneapolis VA Medical CenterInder Anand, MD, FACC, FRCP, DPhil
Director of the Heart Failure Program
Minneapolis VA Medical Center

Inder Anand, MD, FACC, FRCP, DPhil, is Professor of Medicine at the University of Minnesota. Dr. Anand is also Director of the Heart Failure Program at the Minneapolis VA Medical Center. Dr. Anand has expertise in pathophysiology and management of heart failure. He has been a principal investigator...

GLG NewsSMAnalyses by this Study Group's Leading Experts(?)

Opinions and analyses expressed in GLG News are solely those of the author. See the Terms of Use for details.
Oral Treprostinil: An effective medicine hiding in a study with a challenging design? | 11-18-2008
Author: Robert Aris, MD, Associate Professor of Medicine, University of North Carolina Chapel Hill - CC

This phase III study was done without the benefit of conventional drug development with Phase I and Phase II studies (which would have provided more information about the effective dose) preceding it because pharmacokinetic date from IV and SC dosing studies were used to extrapolate for the...

Mild PAH improved by early treatment with bosentan | 07-18-2008
Author: Robert Aris, MD, Associate Professor of Medicine, University of North Carolina Chapel Hill - CC

While functional class II (FC II) PAH patients have been included in previous clinical trials, the EARLY trial is the first study to concentrate (ie recruit exclusively) FC II PAH patients.  This is important because the definition of functional class II is that a patient has a sight...

Peer reviewed literature on Ambrisentan, a selective ETRA for PAH | 06-10-2008
Author: Robert Aris, MD, Associate Professor of Medicine, University of North Carolina Chapel Hill - CC

This Circulation paper is the first peer reviewed data on the 2 pivotal Phase III trials on ambrisentan that lead the FDA to approving it for the treatment of PAH in July 2007. This paper is critically important since all new research needs to withstand the rigor of peer-review for...

Thrombus Aspiration in Acute MI | 05-27-2008
Author: GLG Expert Contributor

Mechanical thrombectomy of the coronary arteries has becoming increasingly more common with the advent of simpler aspiration catheters.  Although its use in the setting of acute myocardial infarction is even more common, it is not routine.  Randomized data indicating its effect on clinical...

Promising results for tekturna | 05-27-2008
Author: GLG Expert Contributor

Novartis was able to show that combining tekturna with HCTZ provided significant improvement in blood pressure and did so safely.  They also showed that it provides better 24 hour coverage and coverage if patients miss a dose or take it late, this is a significant improvement over its competitors...

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