GLG News by Xolair Prescribers for Asthma (US)
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July 2, 2008They'll fix this before the end of the month
Analysis of: Medicare fees to doctors fall Tuesday | news.yahoo.com
Author: David Engler, Physician, The Allergy Clinic
If this isn't fixed, it won't be long before cognitive specialties, like internal medicine and neurology, start capping their practices and not allowing new Medicare patients.
July 2, 2008This may have a market after all
Analysis of: Taro Receives Final FDA Approval For RX Cetirizine Hydrochloride Syrup ANDA | www.medicalnewstoday.com
Author: David Engler, Physician, The Allergy Clinic
Here comes a prescription version of generic Zyrtec syrup. At first glance, we wonder how it will compete with over the counter Zyrtec. But wait...there may be a market for this drug
June 18, 2008Next-Generation Xolair (omalizumab) sounds pretty good
Analysis of: Investigational Anti-IgE Antibody Promising as Extracorporeal Allergy Therapy | www.medscape.com
Author: David Engler, Physician, The Allergy Clinic
This drug seems much more effective at reducing free-IgE levels than is Xolair. Overall, Xolair has given many patients a tremendous improvement in their quality of life, but it hasn't fulfilled many of its promises. Frankly, some of Xolair's benefits are disappointing, particularly in the 40...
June 10, 2008
Will Xolair Become Obsolete in the Treatment of Allergies?
Analysis of: Investigational Anti-IgE Antibody Promising as Extracorporeal Allergy Therapy | www.medscape.com
Author: Mark Vandewalker, Allergy Specialist and Partner, Allergy & Asthma Consultants Of The Ozarks Ltd
Will Xolair Become Obsolete in the Treatment of Allergies?
Analysis of: Investigational Anti-IgE Antibody Promising as Extracorporeal Allergy Therapy | www.medscape.com
Author: Mark Vandewalker, Allergy Specialist and Partner, Allergy & Asthma Consultants Of The Ozarks Ltd
This recent report characterizes a newly discovered anti-IgE monoclonal antibody (mAb12) which appears dramatically more potent than omalizumab (Xolair) in its ability to reduce systemic IgE levels. If further studies confirm this enhanced reduction of IgE and IgE-bearing cells, mAb12 has significant...
April 4, 2008Xyzal--Just overpriced Zyrtec
Analysis of: New antihistamine gets FDA green light.(RX CARE)(Levocetirizine (Xyzal) by UCB Inc. and Sanofi-Aventis ) | www.therapeuticsdaily.com
Author: David Engler, Physician, The Allergy Clinic
A bottle of 30 Generic Zyrtec can be purchased for $15. No one is going to get Xyzal that inexpensively. There are no head to head studies showing Xyzal to be better than Zyrtec. Even though Xyzal claims a 6% sedation rate compared to Zyrtec's 14% rate, it's not apples to apples. ...
April 4, 2008Slowly but surely, Primary Care gets the message about preventing asthma
Analysis of: FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11 | www.pipelinereview.com
Author: David Engler, Physician, The Allergy Clinic
Use of Asmanex will continue to increase with this approval down to age 4. Its dose counter tells you exactly how many doses are left in the device. Pulmicort uses a system that counts down 120---90---60---30---0. A lot of patients on Pulmicort complain to me about this "approximate" dose...
April 4, 2008Singulair increases risk of Suicide? Don't just poo-poo the possibility
Analysis of: FDA Investigating Possible Link Between Singulair and Suicide | www.foxnews.com
Author: David Engler, Physician, The Allergy Clinic
It is difficult to imagine why taking Singulair would increase the risk that someone would complete suicide. After all, what does a leukotriene receptor antagonist have to do with mental health? I don't know. But doctors, ask yourself, have you ever had a Singulair patient stop taking it...
April 2, 2008
Singulair suicide story won't kill Merck
Analysis of: FDA Investigating Possible Link Between Singulair and Suicide | www.foxnews.com
Author: Michael Wechsler, Associate Physician in Pulmonary and Critical Care, BRIGHAM AND WOMEN'S HOSPITAL
Singulair suicide story won't kill Merck
Analysis of: FDA Investigating Possible Link Between Singulair and Suicide | www.foxnews.com
Author: Michael Wechsler, Associate Physician in Pulmonary and Critical Care, BRIGHAM AND WOMEN'S HOSPITAL
Singulair helps millions of people suffering from asthma. While there are a few sporadic cases of suicide and depression among the millions of patients taking singulair, no causal link has been established and there is no clear mechanism of how singulair might even cause such effects. In fact,...
January 23, 2008Alvesco... Finally, a Safe inhaled steroid
Analysis of: ALVESCO(R) gains FDA approval for the U.S. market | www.pipelinereview.com
Author: David Engler, Physician, The Allergy Clinic
State of the art care for asthma over the past 20 years has involved giving the patient steroids to treat "late phase asthma", the mucus, edema and inflammation that happens on the INSIDE of the airways. Alvesco is different from every inhaled steroid that has come before it. It is less likely...
October 8, 2007
IV ZYFLO- GREAT POTENTIAL IN ER, BUT WILL THEY MARKET IT WELL?
Analysis of: Critical Therapeutics Initiates Phase II Clinical Trial for Zileuton Injection | www.pipelinereview.com
Author: Michael Wechsler, Associate Physician in Pulmonary and Critical Care, BRIGHAM AND WOMEN'S HOSPITAL
IV ZYFLO- GREAT POTENTIAL IN ER, BUT WILL THEY MARKET IT WELL?
Analysis of: Critical Therapeutics Initiates Phase II Clinical Trial for Zileuton Injection | www.pipelinereview.com
Author: Michael Wechsler, Associate Physician in Pulmonary and Critical Care, BRIGHAM AND WOMEN'S HOSPITAL
Zyflo is a great drug in its oral fornmaulation with goiod efficacy but has failed because one has to take it multiple times a day and because one has to monitor liver function. This new IV formulation should be as effective in the ER setting, but hurdles include poor drug marketing by Critical Therapeuitcs...
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