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Sunil DhawanJune 25, 2008
Allergan's acquisition of Aczone- is this significant?
Analysis of: Allergan Aquisition of Aczone | agn360.client.shareholder.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article is important in that this acquisition is the first new product for Allergan's dermatology division in several years. This is also the first novel molecule in 5-7 years that has been released. The issues of having to get blood tests with this topical agent have been solved. The obvious paring...
June 23, 2008
It's All in the Eyes
Analysis of: Putting ‘You Look Tired’ to Rest | www.nytimes.com
Author: GLG Expert Contributor
- Dark circles underneath the eyes give the unappealing impression of exhaustion. Many factors, both hereditary and environmental, can produce or exacerbate this condition.  - Despite efforts to address this unmet need, the over-the-counter cosmetic industry has not been able to address consumer's...
May 23, 2008
safety concern with chinese drugs
Analysis of: China Muscles In On The Generics Industry | www.pharmalot.com
Author: GLG Expert Contributor
How can safety be verified with the Chinese history of contaminants in the toy and food industries.  I certainly would not want to take Chinese drugs. lynn tucker
Sunil DhawanMay 19, 2008
This article may change atopic dermatitis treatment by pediatricians
Analysis of: Guidelines Issued for Treating Atopic Eczema in Children | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article is important in that it is a good summary of the current knowledge and treatment methods for atopic dermatitis for pediatricians. It is needed in that this condition is inadequately treated, and a periodic refresher is needed for all physicians. Both pharmacologic and non pharmacologic...
Sunil DhawanMay 19, 2008
Unlicensed person injecting silicone unlikely to impact filler market
Analysis of: Renal Failure Linked to Cosmetic Soft-Tissue Filler Injections | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
This article is important in that it makes the public aware that they should avoid all unlicensed persons who re injecting any substance into their bodies. These especially include those injecting silicone mixtures. The public will become more aware and should have more confidence in licensed practitioners...
Sunil DhawanApril 1, 2008
Long term use of Allergan's Botox does not decrease efficacy
Analysis of: Efficay of Bolinum toxin does not sag over time | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
 This article is important in that it lays to rest a misconception that long term repeated use of Botox ( Allergan) leads to decreased efficacy. Efficacy was maintained, and no neutralizing antibodies were found to Botox. This will reassure most users of Botox, and patients as well.
Sunil DhawanApril 1, 2008
Serious Skin Reactions with TNF antagonists
Analysis of: Serious Skin Reactions with TNF antagonists | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
 This article is important in that it defined the incidence of serious skin reactions to the three common TNF antagonists- Enbrel, Humira, and Remicade. The incidence is relatively low in comparison to the numbers of patients treated. Any foreign protein has the potential for eliciting these reactions,...
Sunil DhawanMarch 31, 2008
AN2728 phase 2a results encouraging.
Analysis of: Anacor Pharmaceuticals Announces Positive Results from Phase 2A Clinical Trial of AN2728 in Psoriasis Patients | www.pipelinereview.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Anacor's recent release of the data from their phase 2a study of AN 2728  for psoriasis were encouraging.  Over 69% actively treated plaques of psoriasis improved versus only 6% of placebo treated plaques. The study was limited by the short duration- only 28 days versus up to 16...
Sunil DhawanMarch 31, 2008
Psoriasis associated with comorbidities- Is this to be expected?
Analysis of: Research Shows Patients With Psoriasis at Increased Risk for Developing Other Serious Medical Conditions | www.pharmalive.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
 This article is important in that it is one of the first to confirm what is  a widely held belief among many dematologists who treat many patients with psoriasis. Specifically that these patients suffer a higher rate of cardiovascular diseases, depression, malignancy, etc. This makes perfect...
Sunil DhawanMarch 19, 2008
Ustekinumab shows promise
Analysis of: Novel Biologic Agent Proves Highly Effective in Severe Plaque Psoriasis | www.medscape.com
Author: Sunil Dhawan, Clinical Assistant Professor of Dermatology, Stanford University
Centocors new product- Ustekinumab /CNTO 1275 had impressive results in the recent PHOENIX trials and the application is under review at the FDA. The PASI score reductions are superior to the exiting agents such as Enbrel and Humira, and are comparable to those of the other Centocor product- Remicade...

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