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GLG News by Ultane Users: Anesthesiologists (US)

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May 15, 2008
Production techniques cause unsafe heparin to be spread through the world resulting in mortality
Analysis of: U.S. Identifies Tainted Heparin in 11 Countries | www.nytimes.com
Author: GLG Expert Contributor
The issues are several: A wave of disease infected and killed many Chinese pigs (whose intestines are raw source material for heparin) and this drove up prices while decreasing supply. Heparin is a low cost, generic drug requiring an extremely tight supply chain to keep costs down.  ...
May 15, 2008
POISE shows high-dose beta blockers reduce heart attacks but cause more harm than good overall.
Analysis of: Higher Risk of Death and Stroke in Patients Given Beta Blockers After Non-Cardiac Surgery (POISE Trial) | pharmalive.com
Author: GLG Expert Contributor
This study again showed reduced cardiac events with peri-operative beta blockers.   However, patients had higher overall mortality from all causes relative to placebo.  Increased stroke rates provide some explanation. This study used a starting dose 8 times recommended.  Previous studies...
December 6, 2007
The impact in disease prevention efforts is how you identify root problems
Analysis of: CBO: Medicare and Medicaid spending growth unsustainable | www.ama-assn.org
Author: GLG Expert Contributor
Medicare and Medicaid today are predominantly reactive disease diagnosis and management programs, usually in late stages. That form of care leads to the significant growth of healthcare expenditure (currently estimated at 8% GDP). The future of cost control is disease prevention. Many diseases are only...
October 29, 2007
The impact of HSD1 inhibitor on decreasing diabetes, hypertension, obesity, heart disease and their complications
Analysis of: Vitae Pharmaceuticals and Boehringer Ingelheim announce a major collaboration to develop and commercialize novel treatments for diabetes and metabolic diseases | www.pipelinereview.com
Author: GLG Expert Contributor
The development of HSD1 inhibitors respresents a promising advance in managing diabetes and the metabolic syndrome comprising of obesity, hypertension, and difficult regulation of serum glucose levels. Control of the problems of diabetes and the metabolic syndrome would compose the major components...

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