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December 1, 2008
Financial analysis of the Gardasil-for-Guys question
Analysis of: Gardasil, Merck's Cervical Cancer Vaccine, Demonstrated Efficacy in Preventing HPV-Related Disease in Males in Phase III Study | www.fiercebiotech.com
Author: GLG Expert Contributor
Everyone who expects Gardasil to be approved for general use in males may be very surprised.  Yes, Gardasil prevents HPV in males, but the cost/benefit ratio is completely off compared to women.  The cost is MUCH higher per case of invasive HPV prevented and the benefit is much lower for penile...
November 18, 2008
Gardasil for selected men only
Analysis of: Gardasil, Merck's Cervical Cancer Vaccine, Demonstrated Efficacy in Preventing HPV-Related Disease in Males in Phase III Study | www.fiercebiotech.com
Author: GLG Expert Contributor
-Gardasil has been shown effective in men to prevent infection with high-risk HPV subtypes.  This is great news for some men. -Gardasil when given to all women (now currently in roll-out) will interrupt heterosexual HPV transmission.  Sexually active gay/bisexual males will benefit...
November 10, 2008
ER testing for HIV: does anyone else see a problem with this?
Analysis of: Rapid HIV Testing in the ER Boosts Diagnoses, Screening | www.medcompare.com
Author: GLG Expert Contributor
-I'm thrilled to see that a provider evaluating someone for an STD also tests for HIV -but- -I'm appalled that people can be seen in an ER for a suspected STD, just like I would be for those that go for colds and ear infections.  How much did each of those chlamydia and gonorrhea and syphilis...
November 4, 2008
Your doctor doesn't get a flu shot WHY????
Analysis of: Flu shots a tough sell to health care workers | ap.google.com
Author: GLG Expert Contributor
-A recent informal survey found that many docs and nurses (60% of healthcare workers overall) don't get an annual flu vaccine, despite proven efficacy, easy availability at their place of work, and risk of contagion to patients and colleagues.  -This puts some of the most...
November 3, 2008
Parental "choice" against flu vaccine would be unwise
Analysis of: Flu Vaccine for Preschoolers | www.nytimes.com
Author: GLG Expert Contributor
-Parents in NJ are fighting a new state mandate requiring influenza vaccine in preschoolers -Allowing an override of this mandate would be dangerous but parents will have only themselves to blame if their unvaccinated kids get sick
November 3, 2008
Rotavirus vaccine delivers
Analysis of: Vaccine Slashes Diarrheal Ilness in Kids | www.nytimes.com
Author: GLG Expert Contributor
Rotateq is a great vaccine - it protects both vaccinated patients and also gives some protection to their not-yet-vaccinated peers Although in the US it is rare to die from rotavirus illness, the economic savings on lost school/work days and decreased hospital admissions and ER visits is huge.
November 3, 2008
Stockpiling flu vaccines at home will never make sense given Americans' sensibilities
Analysis of: U.S. looks at whether home drug stockpiles for flu pandemic makes sense | canadianpress.google.com
Author: GLG Expert Contributor
Most American families are not familiar with signs and symptoms of influenza.  Asking them to use (and not use) a home supply of antivirals would be insanity, stretching thin the amount of antivirals available and depriving them to those in true need.  To ask them to use these meds appropriately...
June 30, 2008
Who cares?
Analysis of: Taro Receives Final FDA Approval For RX Cetirizine Hydrochloride Syrup ANDA | www.medicalnewstoday.com
Author: GLG Expert Contributor
Taro just got approval for Rx cetirizine - big whoop!  Zyrtec has been OTC in all forms (tablet, chewable and syrup) since 11/07.  Do you know anyone who will write a prescription for an OTC drug or an insurance company that will cover it?
June 27, 2008
GSK completes pediatric DTP+ line with (awfully named) Kinrix
Analysis of: FDA Approves GlaxoSmithKline's New Combination Vaccine For Children | www.medicalnewstoday.com
Author: GLG Expert Contributor
Glaxo has just gotten approval for Kinrix (DTaP-IPV).  It's products for infants and toddlers, Pediarix (DTaP-HepB-IPV) and Infanrix (DTaP) are used in children under 2; Kinrix will be used for the 4-6 year booster dose, reducing by 1 the number of vacthat children get at this age.
June 11, 2008
BPA uncertainty will cause short-term opportunity regardless of ultimate conclusions
Analysis of: FDA's Chief Scientist Asks Science Board Subcommittee To Review Research On Bisphenol-A | www.medicalnewstoday.com
Author: GLG Expert Contributor
The FDA is opening investigations into whether the widely used plastic additive bisphenol A may have various effects on humans, based on animal models. Several companies are already touting their "BPA-free" status; as the FDA investigation will take a prolonged period to review and summarize available...

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