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GLG News by Silicone Hydrogel and Bausch and Lomb Contact Lens Prescribers: Ophthalmologists and Optometrists (US)

Analysis of: Genentech revisits plan for Avastin (www.sfgate.com)
In the two weeks since Genetech made its announcement that it would limit the availability of Avastin to ophthalmologists for use in treating wet macular degeneration the outcry from patients, ophthalmologists, politicians, and the American Academy of OPhthalmology has been so great that Genetech is...
Analysis of: Ophthalmologists Concerned About AMD Patients’ Access To Avastin (aao.org)
The American Academy of Ophthalmology said the recent decision by Genentech to limit availability of Avastin (bevacizumab) to compounding pharmacies could have a significant negative impact on the care of patients with age-related macular degeneration [AMD]. Dr. Charles Wilkinson, president of the AAO,...
Analysis of: Genentech to cease supplying bevacizumab to compounding pharmacies (www.osnsupersite.com)
Genentech, Inc.  is suspending sales of Avastin (bevacizumab) to compounding pharmacies in the United STates, in an effort to curb its non approved use for wet macular degenration. Recently, ophthalmologists have begun using the antiangiogenic cancer drug off-label to treat retinal neovascularization...
Analysis of: Alacrity Biosciences Announces Positive Results from a Phase 2 Study of Its Dry Eye Treatment ALTY-0501 (www.pipelinereview.com)
Alacrity Biosciences has completed a Phase 2 clinical trial of ALTY-1501, an eye drop for the treatment of dry eye. Dry eye (or keratoconjunctivitis sicca (KCS) affects more than 10% of the US population and its incidence is increasing as baby boomers become senior citizens. Although the small...
Darcy Ryan, OD, Optometrist
Hertzog Eye Associates
Analysis of: A New Silicone Hydrogel Lens Comes to Market (www.clspectrum.com)
The newest silicone hydrogel contact lenses introduced to the market use a siloxane-based material, and include the Ciba O2 Optix Custom, the Coopervision Biofinity, and now the Menicon PremiO.  I have yet to get my hands on and prescribe any of these lenses so I don't have any first accounts...
Analysis of: Maker Seeks to Restrict Cancer Drug Used on Eye (www.nytimes.com)
       Genentech has had first year revenues of $800 million from its drug Lucentis, which is used intravitreaaly to treat macular degeneration on label and some other conditions off label.   Although this amount of sales places Lucentis well within the blockbuster...
Steve Rubinstein, OD, Optometrist
Steve Rubinstein, OD, Optometrist
Sound Shore Vision Care
Analysis of: Maker Seeks to Restrict Cancer Drug Used on Eye (www.nytimes.com)
How much should packaging of a drug cost?
Gary Barker, Partner/Owner
Gary Barker, Partner/Owner
Eye Associates Of Winter Park
Analysis of: Targeting amyloid- b in Glaucoma (www.pnas.org)
To delve further into the reasons for retinal ganglion cell death is critical for the future of glaucoma treatment. As the article discusses, there are reasons for retinal ganglion cell death other than high intraocular pressures.  Unfortunately, the only medical and surgical methods we have...
Analysis of: IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth (www.pnas.org)
Omega-3 supplementation could be a useful strategy for protecting against retinopathy of prematurity (ROP), say Swedish investigators. In the study, mice with retinopathy were fed food enriched with either omega-3 or omega-6. Mice that ate omega-3 initially lost fewer retinal blood vessels than mice...
Analysis of: Blood Pressure, Arterial Stiffness, & Open Angle Glaucoma: The Rotterdam Study (archopht.ama-assn.org)
Patients with high arterial pulse pressure may be at increased risk for high-tension open angle glaucoma, a Dutch study concludes. Researchers analyzed data from 5,317 individuals, 215 of who had definite or probable open-angle glaucoma and 5,102 of whom were disease free.The analysis found that high-tension...

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