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GLG News by Restylane Users for Wrinkles: Dermatologists

Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Nephrogenic Fibrosing Dermopathy Associated with Exposure to Gadolinium-Containing Contrast Agents (www.medscape.com)
This and other studies are highly suggestive that Gadolinium agents used in radiographic studies are associated with NFD. A large scale study should be initiated to confirm this association, and for now these agents should be avoided in patients with renal disease.
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Black Box Warning for Topical Calcineurin Inhibitors and the Death of Common Sense (www.medscape.com)
I totally agree with this article. The conclusions from the FDA are incorrect, and the data appear to indicate that the TCI's are actually protective!!!! In any event it has created a false sense of a problem, where none exists, and decreases the use of these agents, which are safer than the existing...
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Treatment of Acne Scarring (www.medscape.com)
This article is a good summary of the currently available techniques of excision, subcision, and resurfacing. It does not mention dermal grafting, a technique that I personally use quite often. The maximum correction that one can achieve is 50-70% with a combination of multiple techniques.
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Cytochroma Completes Enrollment In Phase II Psoriasis Trial (www.pipelinereview.com)
This product by Cytochroma is a vitamin D analog which is similar to Dovonex, a product that has been used for 13 years. Its efficacy is modest at best. This product may, repeat may be better, because it activates the vitamin D pathway, and inhibits catabolism of Vitamin D. Whether this makes the product...
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Blast Away Wrinkles (www.ivanhoe.com)
This technology is new, but no better than other resurfacing technologies like Sciton and Fraxel. Pain is significant, healing takes weeks, and there are risks as in other resurfacing technologies. The final results are good. A head to head comparison with other technologies is needed.  
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Proof Nailed Down that Antibiotics Use Leads to Resistance (www.medpagetoday.com)
This article has validity in dermatology due to the increased resistance seen in acne. This may have clinical significance in that we may be seeing resistance to therapy in acne patients  after prolonged use.Collagenex corp. is developing non antibiotic medications for acne and rosacea that are...
March 12, 2007
No downtime is king
Analysis of: New Survey Reveals Dramatic Rise in Non-Invasive Procedures in Facial Plastic Surgery (www.surgicenteronline.com)
1. It underlines the fact that aesthetic procedures are increasingly accepted and accessible to the general public2. It gives indications about the qualities to look for on new technologies and procedures in order to make them marketable.  
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Allegiance Equity Corporation Announces Positive Results of In Vitro Studies and an Open Label Trial for Relieva(R) in Treating Atopic Dermatitis (www.pipelinereview.com)
The open label trial results for the product Relieva from Allegiance Equity Corp. are encouraging. However the trials need to be double blinded, and with a much larger number of patients. If the product can be compared to a low- mid potency topical steroid in efficacy, then it will be successful. Homeopathic...
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Sunil Dhawan, MD, Clinical Assistant Professor of Dermatology
Stanford University
Analysis of: Basilea Reports Positive Phase III Results for Alitretinoin (www.pipelinereview.com)
This large phase 3 trial for Alitretinoin results are significant in the this would be the first oral agent specifically for resistant hand dermatitis. the results are positive with good significance. The major problem will be getting the FDA  to accept the drug without the onerous pregnancy prevention...
Analysis of: Nonsurgical wrinkle filler wins by a nose (www.shreveporttimes.com)
1. The non-surgical market is growing because people wishes to find alternatives to surgical procedures.2. I use Radiesse and also believe is an excellent product, although you can achieve same results as the article describes with any long lasting hyaluronic acid gel.

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