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GLG News by Refractive Surgeons (US)

Analysis of: Novagali Pharma Announces FDA Clearance of IND for US Pivotal Phase III Trial of Nova22007 for Treatment of Dry Eye Syndrome (www.pipelinereview.com)
The current paradigm of Dry Eye disease revolves around inflammation as a key and essential component in its development and progression. Many current and developing regimens (artificial tears, secretagogues such as Ecabet sodium and diquafosol and 15-HETE, mucomimetics such as Milicin, etc...) do...
Analysis of: Toric lens approval unlikely this year, STAAR Surgical says (www.ophthalmologytimes.com)
For a company that has had its share of rejections and problems with the approval of a phakic IOL (ICL Visian)  that it tried to have enter the US market almost a decade ago, things are not improving much for Staar.  The company recently reported that despite its request over one year ago...
Analysis of: Better Vision Without Looking Your Age (www.nytimes.com)
Mutifocal iols are currently used to try to correct distance and near vision.  While patients are often pleased by their improved near vision without glasses, many complain of poor optical quality for distance vision.  Due to great out of pocket costs and poor quality of vision under some...
Analysis of: Researchers report 13 cases of MRSA keratitis after laser refractive surgery (www.osnsupersite.com)
These cases may just be an isolated incident and the report of one or two cases clearly creates attention to the infection and awareness for further cases. In the over 11 years since laser vision correction has been approved in the USA we have not seen much incidence of these infections, so we must...
April 16, 2007
Now Hold On!
Analysis of: LASEK effectively treated post-LASIK myopic regression in study (www.osnsupersite.com)
An argument can be made for LASEK over LASIK for the initial laser treatment in some patients, but the re-lifting of the lasik flap and performing a laser re treatment is the management of choice in almost all cases of post lasik myopic regression. An exception would be if the cornea is too thin or...
Barry Schechter, MD, Director of Corneal and External Diseases
Barry Schechter, MD, Director of Corneal and External Diseases
Florida Eye Microsurgical Institute, Inc.
Analysis of: Researchers report 13 cases of MRSA keratitis after laser refractive surgery (www.osnsupersite.com)
Refractive surgery is taken for granted by patients to "get rid of their glasses and contact lenses". They rarely consider the possibility of loss of vision.
Analysis of: Positive Interim Phase 2 Data Reported for VEGF Trap-Eye in Age-Related Macular Degeneration (www.pipelinereview.com)
    The VEGF Trap from Regeneron is a protein made up off human VEGF receptors fused to human immunoglobulin.  This compound binds VEGF, preventing VEGF from binding to its natural receptors, interrupting the angiogenic cascade.    The phase II study showed promising...
Sanjay Rao, MD, Medical Director
Sanjay Rao, MD, Medical Director
Lakeside Eye Clinic
Analysis of: Retinal specialist on the Avastin/Lucentis Controversy (patentdocs.typepad.com)
This article describes the perspective of a retinal specialist on the Avastin/Lucentis controversy.  In mid-February the National Institutes of Health announced that it would conduct a head to head trial comparing the effectiveness of Lucentis and Avastin for the treatment of wet  age...
Sanjay Rao, MD, Medical Director
Sanjay Rao, MD, Medical Director
Lakeside Eye Clinic
Analysis of: Better Vision Without Looking Your Age (www.nytimes.com)
This New York Times article describes many of the vision correction options available to individuals with presbyopia.  Because of the growing population of baby boomers, there is significant public interest in options that allow individuals freedom from reading glasses.  Multifocal contact...
Sanjay Rao, MD, Medical Director
Sanjay Rao, MD, Medical Director
Lakeside Eye Clinic
Analysis of: AquaLase shows trend toward less foveal thickening in diabetic patients (www.osnsupersite.com)
This article presents the results of a study comparing standard phacoemulsification to Aqualase.  Complication rates were similar between the two procedures.  The 63 patient study looked in particular at foveal thickening after surgery.  While no statistical significance was demonstrated,...

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