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GLG News by Radiologists in the US who use Nighthawk Radiology Services

Marc Hamet, MD, President
Marc Hamet, MD, President
Image Guided Therapeutics, LLC.
August 21, 2008
Its all about the spin
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time (www.bloomberg.com)
This article could easily be spun as a victory for stent efficacy.
Analysis of: 8-Year-Olds on Statins? A New Plan Quickly Bites Back (www.nytimes.com)
Widespread use of statins is likely to reduce the incidence of heart attacks and strokes and reduce the process responsible: atherosclerosis. Statins are expensive and selection of individuals and children at high to moderate risk should go beyond risk stratification by standard means and...
Analysis of: Look to England's example for ways to solve America's health-care problem (www.sltrib.com)
A single payer, national system does work, but may not necessarily be in the best interest of all parties.   Yes this type of system is 'free' to the users, but is funded through higher taxes than paid in the US.
Analysis of: NeuroSearch initiates pivotal Phase III programme with ACR16 for the treatment of Huntington’s disease (www.pipelinereview.com)
ACR16 is part of a class of drugs called dopaminergic stabilizers. These drugs modulate the effect of dopamine (a neurotransmitter secreted naturally by the brain). While more effects and interactions related to dopamine are constantly being discovered, it is known that dopamine plays a role in movement...
Analysis of: FDA Provides Clarity to Isis Regarding the Development Path for Mipomersen (www.pipelinereview.com)
Mipomersen (formerly known as ISIS 301012) is a in class of novel therapeutic agents that reduce the production of a protein in the liver that is responsible for cholesterol production. It is though that inhibiting that production on a molecular level would decrease the levels of cholesterol. Mipomersen...
Analysis of: Micromet Enrolls First Patient in Phase 1 Clinical Trial with MT110, the First BiTE Antibody for Treatment of Solid Tumors (www.pipelinereview.com)
Antibodies are formed by the bodies own immune system to any foreign substances it encounters. Tumors are considered by the body to be foreign at it often requires a genetic mutation for cells to become cancerous. Cancers are able to circumvent these natural antibodies by various means but there is...
Analysis of: GlaxoSmithKline to acquire Sirtris Pharmaceuticals, a world leader in 'Sirtuin' research and development (www.pipelinereview.com)
Situins are enzymes that regulate predetermined cell death, activity in muscle and fat cells as well as energy expenditure. There are several classes of these enzymes (SIRT 1 through 7). The technology is promising in that it promises to regulate some of the causes of diabetes and obesity rather than...
Analysis of: GlaxoSmithKline and Regulus Therapeutics form strategic alliance to develop microRNA targeted therapeutics to treat inflammatory diseases (www.pipelinereview.com)
MicroRNA and their related cousins small interfering RNA, are small molecules that operate in cell regulation. As such they have function in cancer, inflammatory disease, heart and kidney disease.
Analysis of: Roche fully acquires privately-owned biotech company Piramed (www.pipelinereview.com)
PI 3-kinases are enzymes that play a role in the functioning of cells and their response to stimuli. In essence, these enzymes form portions of the ‘production line’ in cells. Turning up the tempo in this 'production line' is though to play a role in cancer growth and uncontrolled inflammation...
Analysis of: MedImmune Advances Asthma Program with Start of a Phase 2 Trial in Europe and Australia and First U.S.-Based Clinical Trial for Antibody Targeting IL-13 (www.pipelinereview.com)
Interleukins (IL's) are a family of mediators that play a part in the inflammatory response. As such they play a role in asthma and other allergic disorders. There are at least 29 interleukins known of which three types are currently being targeted by Medimmune (a division of Astra).

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