The Expertise Imperative and Compliance Technology
Access to a diverse array of specialized expert inputs drives superior decisions in every organizational context: within corporations, by investors and consultancies, and within nonprofits. When decision makers are confident of their decision inputs, they can respond more quickly and creatively to challenges and opportunities.Learn more about GLG's Compliance Framework
This page may include content provided by Council Members, your access to which is subject to the Terms of Use.
Widespread use of statins is likely to reduce the incidence of heart attacks and strokes and reduce the process responsible: atherosclerosis. Statins are expensive and selection of individuals and children at high to moderate risk should go beyond risk stratification by standard means and...
A single payer, national system does work, but may not necessarily be in the best interest of all parties. Yes this type of system is 'free' to the users, but is funded through higher taxes than paid in the US.
ACR16 is part of a class of drugs called dopaminergic stabilizers. These drugs modulate the effect of dopamine (a neurotransmitter secreted naturally by the brain). While more effects and interactions related to dopamine are constantly being discovered, it is known that dopamine plays a role in movement...
Mipomersen (formerly known as ISIS 301012) is a in class of novel therapeutic agents that reduce the production of a protein in the liver that is responsible for cholesterol production. It is though that inhibiting that production on a molecular level would decrease the levels of cholesterol. Mipomersen...
Antibodies are formed by the bodies own immune system to any foreign substances it encounters. Tumors are considered by the body to be foreign at it often requires a genetic mutation for cells to become cancerous. Cancers are able to circumvent these natural antibodies by various means but there is...
Situins are enzymes that regulate predetermined cell death, activity in muscle and fat cells as well as energy expenditure. There are several classes of these enzymes (SIRT 1 through 7). The technology is promising in that it promises to regulate some of the causes of diabetes and obesity rather than...
MicroRNA and their related cousins small interfering RNA, are small molecules that operate in cell regulation. As such they have function in cancer, inflammatory disease, heart and kidney disease.
PI 3-kinases are enzymes that play a role in the functioning of cells and their response to stimuli. In essence, these enzymes form portions of the ‘production line’ in cells. Turning up the tempo in this 'production line' is though to play a role in cancer growth and uncontrolled inflammation...
Interleukins (IL's) are a family of mediators that play a part in the inflammatory response. As such they play a role in asthma and other allergic disorders. There are at least 29 interleukins known of which three types are currently being targeted by Medimmune (a division of Astra).