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GLG News by Psychiatrists

Louis Sanfilippo, MD, President
Louis Sanfilippo, MD, President
LCS Group, LLC
Analysis of: FDA Approves Luvox CR (Fluvoxamine Maleate) Extended-Release Capsules for the Treatment of Social Anxiety Disorder and Obsessive Compulsive Disorder (pharmalive.com)
Fluvoxamine, the least known of the selective serotonin reuptake inhibitors in the US, will now have an FDA approved controlled release version - Luvox CR - for the treatment of OCD and Social Anxiety Disorder.   The collaboration between Jazz Pharmaceuticals and Solvay will have only an uphill...
Louis Sanfilippo, MD, President
Louis Sanfilippo, MD, President
LCS Group, LLC
Analysis of: St. Jude Medical Announces Clinical Study of Deep Brain Stimulation for Depression (www.pipelinereview.com)
Deep brain stimulation (DBS), an FDA approved device treatment for Parkinson’s Disease and essential tremor, has demonstrated quite remarkable findings in several very small pilot studies for treatment resistant depression.   There is great hope among the device makers – namely Medtronics...
Analysis of: Evotec Starts Phase II in Smoking Cessation with EVT 302 (www.pipelinereview.com)
Smoking cigarettes is a serious health problem throughout the world and smoking cessation is an important clinical problem.  Stopping smoking is tremendously difficult for some because of the highly addictive nature of nicotine, but also because of the predominant use of smoking as a form of self-medication...
Analysis of: British Study Says Anti-Depressants Are Useless (www.furiousseasons.com)
I believe publications such as these are probably useful reactions to over-prescribing antidepressants for anything that ails you (which is what has been occuring until the recent suicide scare in adolescents).  Nevertheless, such generalizations have significant influence even though they are...
Analysis of: Google to store patients' health records (news.yahoo.com)
The news is adding an interesting angle to patient's access to personal health information from an internet-based company- Google, a break from the conventional practice to keep patients health record with health agencies.  This venture from Google can be attractive to many people, although...
Analysis of: New Novartis Research Institute first to focus on innovative vaccines for the developing world (www.pipelinereview.com)
This artcle is a brief summary of a promising step by New Novartis Research Institute to provide a platform to delivering vaccines to diseases, particularly specific to developing countries. This pragmatic attitude to serve the unmet needs of the developing countries is expected to provide...
Louis Sanfilippo, MD, President
Louis Sanfilippo, MD, President
LCS Group, LLC
Analysis of: Memory Pharmaceuticals & Roche Expand Development Program for MEM 3454 in Schizophrenia (www.pipelinereview.com)
The announcement of this small biomarker study for MEM 3454, an alpha-7 neuronal nicotinic receptor (NNR) partial agonist in joint development by Memory Pharmaceuticals and Roche for the treatment of cognitive impairment associated with schizophrenia (CIAS), seems like a step in the right direction...
Analysis of: Daring to Think Differently About Schizophrenia (www.nytimes.com)
Based on Lilly's early results, it is too soon to tell if its glutamate medication will achieve clinical utility.
Analysis of: Daring to Think Differently About Schizophrenia (www.nytimes.com)
All currently marketed antipsychotic medications for treating  schizophrenia  rely on mechanisms of action  which target  dopamine and  serotonin receptors.  Although these medications reduce delusions and hallucinations without inducing symptoms of Parkinson's Disease...
February 26, 2008
THe hoopla is premature
Analysis of: Daring to Think Differently About Schizophrenia (www.nytimes.com)
The clinical trial which was done has shown only comparable efficacy to available treatment for positive symptoms.  It did not study efficacy for cognition or negative symptoms.  It did not test efficacy in treatment resistant patients. It did not show long term efficacy. It did not show that...

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