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GLG News by Psychiatrists (US)

Analysis of: Apple Faces Challenges In Driving iPhone Adoption By Business (www.informationweek.com)
It is only a matter of time, measured in months now, for the Apple Iphone to start treading on Blackberry's Turf.  There are many compelling reasons why this will be inevitable
Analysis of: FDA Approves Luvox CR (Fluvoxamine Maleate) Extended-Release Capsules for the Treatment of Social Anxiety Disorder and Obsessive Compulsive Disorder (pharmalive.com)
OCD (Obsessive Compulsive Disorder) and SAD (Social Anxiety Disorder) are two of the more common...much more common than formerly thought...diagnoses and also two of the most difficult to treat.  JAZZ Pharmaceutical's new fluvoxamine formulation (Luvox CR) will invigorate patient self-identification...
Analysis of: FDA Issues Not-Approvable Letter for Lilly's Zyprexa(R) Long-Acting Injection (LAI) for Schizophrenia Treatment (www.pipelinereview.com)
It is unfortunate that Zyprexa LAI, met with a Non-Approvable Letter, based on a case of delayed sedation reported by Lilly.  However, I would not count this medication out and it would be unfortunate if this were the case.  Several factors argue in favor of eventual approval. 
Analysis of: British Study Says Anti-Depressants Are Useless (www.furiousseasons.com)
Over the last few years there have been various "studies" attempting to prove the thesis that antidepessant medications (SSRI's are usually the focus) are little better than placebos.  This latest salvo will be a very minor blip, not a speed bump.
Analysis of: Daring to Think Differently About Schizophrenia (www.nytimes.com)
Excitement is brewing among the cognoscenti around a new paradigm to treat mental illness, schizophrenia in particular.  The buzzword is glutamate...and early studies show promise...but will the huge investment of resources prove ultimately profitable.
Analysis of: House Moves Closer to Mental Health Bill (online.wsj.com)
Congress is considering legislation to place mental illness on the same footing as other medical disorders.  The parity bills being considered by the House and Senate differ widely in scope.  The resulting legislation will likely affect the insurance coverage of millions of people for many...
Analysis of: FDA Approves Luvox CR (Fluvoxamine Maleate) Extended-Release Capsules for the Treatment of Social Anxiety Disorder and Obsessive Compulsive Disorder (pharmalive.com)
1. Controlled release preparations are often better tolerated with fewer side effects than immediate release preparations 2. OCD and SAD are severe, highly prevalent and chronically disabling conditions 3. Despite presence of SSRIs and other treatment, e.g, cognitive behavioral therapy, up to 1/3 of...
Analysis of: U.S. Food and Drug Administration Approves Abilify (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age) (pharmalive.com)
1. Despite common use of multiple psychotropic medications for bipolar disorder in youth, there are few FDA-approved treatments 2. Abilify is one of the safest and best tolerated of the atypical antipsychotics with fewer side effects than some of the other atypical antipsychotic medications 3. This...
Louis Sanfilippo, MD, President
Louis Sanfilippo, MD, President
LCS Group, LLC
Analysis of: DOV Pharmaceutical, Inc. Initiates Phase II Clinical Trial in Patients With Major Depressive Disorder (www.pipelinereview.com)
Triple-reuptake inhibitors (TRIs) represent an emerging class of antidepressant drugs in development with potential application for other disorders including ADHD and obesity.   By potentiating all three of the main monoamine neurotransmitters implicated in depression  - serotonin, norepinephrine,...
Analysis of: FDA Approves Luvox CR (Fluvoxamine Maleate) Extended-Release Capsules for the Treatment of Social Anxiety Disorder and Obsessive Compulsive Disorder (pharmalive.com)
Luvox was one of the first SSRI's approved for pediatric prescription (for OCD rather than for depression). When patent expired, the maker discontinued manufacture. It has been available in limited supply as generic. Availability of brand-name extended-release product (Luvox CR) will be a significant...

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