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GLG News by Physicians who Treat Schizophrenia (US)

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December 1, 2008
Designing effective medications for populations depends on how easy it is to diagnose the populations.
Analysis of: Personal medicine is goal of Eli Lilly & Co. | www.azcentral.com
Author: GLG Expert Contributor
The article indicates that medications will be designed to be effective for particular populations.  This will prevent the need to try medications which are effective for 50% of the population or less.
November 24, 2008
Efficacy isn't everything
Analysis of: 2nd Generation Antidepressants Prove Effective | health.usnews.com
Author: GLG Expert Contributor
This article tells you only that the drugs are equally effective, but not what that really means in real life.
October 28, 2008
seroquel xl a new formulation
Analysis of: AstraZeneca's Seroquel XL, Once Daily Formula, Now Available For UK Patients | www.medicalnewstoday.com
Author: GLG Expert Contributor
Seroquel is an atypical antipsychotic that has efficacy in 2 very serious mental illnesses- schizophrenia and bipolar disorder. A symptom of both illnesses can be cognitive impairment , confusion, and non-compliance. A once a day formulation of any of their meds helps with compliance and thus maximizes...
October 13, 2008
Just because they say so, it ain't necessarily so.....
Analysis of: St John's Wort 'as good as Prozac' | ukpress.google.com
Author: GLG Expert Contributor
This "report" tells you nothing that you need to know in order to assess the validity of these studies.  We have always known that St. John's Wort has some effectiveness---but it certainly does not come without side-effects.  Where is the information about the length of the studies, the relative...
October 13, 2008
C. difficile not linked to antibiotics will change how I order stool studies
Analysis of: C. Difficile And Antibiotics Not Necessarily Linked, Study Finds | www.sciencedaily.com
Author: GLG Expert Contributor
C. difficile is only linked to antibiotic use about half the time.  In addition c. difficile can complicate IBS more that previously thought.  This may be why antibiotics that cover c. difficile have been useful in treating irritable bowel syndrome.  
October 8, 2008
Interesting, but be cautious
Analysis of: Lilly Announces Initiation of Second Global Phase III Trial of Investigational Alzheimer's Disease Compound | newsroom.lilly.com
Author: GLG Expert Contributor
Gamma secretase inhibitors are one of several kinds of drugs being studied for the prevention/amelioration of Alzheimer's.  In concept they make sense.
October 6, 2008
Clinical Trials Go Unpublished
Analysis of: Many Trial Reports on FDA-Approved Drugs Go Unpublished | www.washingtonpost.com
Author: GLG Expert Contributor
The articles more often go unpublished if the study indicates that there is no benefit to new drugs over older drugs.
October 3, 2008
Heart attack and Cardiovascular disease increased with anticholinergics
Analysis of: COPD Medicines: Risky or Safe? | www.webmd.com
Author: GLG Expert Contributor
How can we best determine if the correlation is a direct cause an effect.  Do the anticholinergics cause increase MI and cardiac disease or do the anticholinergics lead to something else that results in MI and carddiovascular disease.
October 3, 2008
ADHD parent training programs will not likely be effective in the US
Analysis of: Parents 'need lessons about ADHD | news.bbc.co.uk
Author: GLG Expert Contributor
The article summarizes the best treatment for ADHD in children; training the parents and teachers how to more effectively interact with the child.  The article is written for the BBC.
September 11, 2008
Psychiatrists have abandoned therapy
Analysis of: National Trends in Psychotherapy by Office-Based Psychiatrists | archpsyc.ama-assn.org
Author: GLG Expert Contributor
This is hardly news to any practicing psychiatrist. It has become a profession devoid of any meaning. The quality of treatment has deteriorated beyond belief. 

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