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GLG News by Physicians who Treat Neuropathy (US)

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October 11, 2007
Bogus
Analysis of: Burden of diabetes care rivals disease complications | www.reuters.com
Author: GLG Expert Contributor
No implications, except how these patients are receiving intensive insulin therapy may need to be improved.
September 26, 2007
Another "cure" for diabetes?
Analysis of: Bariatric surgery - possible treatment for type 2 diabetes mellitus | www.news-medical.net
Author: GLG Expert Contributor
1. Weight loss may improve carbohydrate metabolism in patients with  Type 2 DM 2. Weight loss is difficult to maintain even in these patients 3. There is more to curing type 2 DM then losing weight
September 26, 2007
Accomplia: Does it accomplish enough?
Analysis of: Sanofi aims to show there's still life in Acomplia | www.reuters.com
Author: GLG Expert Contributor
Weight loss is good but the amount and time to reach goal is more important then just the weight loss potential itself
September 21, 2007
Exubera: To Little , Too Late
Analysis of: New Data Support Long-Term Efficacy and Safety in Patients Who Took Exubera for Eight Years | www.pipelinereview.com
Author: GLG Expert Contributor
Long term studies of Exubera do little to reassure the product's safety. This is especially true in the face of new insulin pens that are safe, effective and makes it very easy to administer insulin.
September 7, 2007
Liraglutide is a small step forward, but there will be bigger steps to come shortly.
Analysis of: Liraglutide improves glucose control and lowers body weight in two phase 3 studies comprising more than 2,000 patients | www.pipelinereview.com
Author: GLG Expert Contributor
Liraglutide will steal some market share from the leader, exenatide, but if exenatide comes out in a once a week formulation and other similar products even less often, the market will shift again.
September 3, 2007
Mitiglinide—Thrice Your Out
Analysis of: Elixir Pharmaceuticals initiates final Phase III clinical study prior to NDA | www.pipelinereview.com
Author: GLG Expert Contributor
Mitiglinide may have a role in specific subtypes of diabetes patients, but it thrice a day dosing in a hurdle for all but the compulsive few.
September 3, 2007
Diabetes Medications Are For Sugars; Statins and Hypertensives Are For Hearts
Analysis of: FDA Adviser Questions Surrogate Endpoints for Diabetes Drug Approvals | www.medpagetoday.com
Author: GLG Expert Contributor
To demand diabetes medications have positive outcomes would be akin to asking for proof that antibiotics save lives or statins lower blood sugars. If this be law, we would have very few drugs and lots of sick patients.
August 27, 2007
The New Medicare Regulations: Realistic or The Beginning of a Witch Hunt
Analysis of: New Medicare Regulations Adopted To Reduce Certain Hospital Infections And Medical Errors | www.medicalnewstoday.com
Author: Abdhish Bhavsar, Owner, Abdhish Bhavsar, MD
The new Medicare regulations are not based in science as there is no proven clear cut medical way to eliminate the incidence of these "so-called" medical errors. It would be a dream to believe that some intervention today can eliminate the occurrence of infections in hospitals or patient falls. ...
August 21, 2007
Avandia And The Story Of Humpty Dumpty
Analysis of: GlaxoSmithKline updates prescribing information for Avandia in the US | www.pipelinereview.com
Author: GLG Expert Contributor
The Black Box CHF Warning for Avandia and Actos, is not new information. It merely defects the real issue-- the risk of overall cardiac events.
August 20, 2007
Vertebroplasty vs kyphoplasty vs arcuoplasty
Analysis of: Medtronic Buys Kyphon For $3.9 Billion | www.forbes.com
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
Will the recent purchase of Kyphon by Medtronic signals the end of kyphoplasty? No because arcuoplasty does not restore vertebral height. Vertebroplasty, kyphoplasty and arcuoplasty essentially achieve the same goals, which brings up the question, do we need all three techniques? Arcuoplasty is the...

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