GLG News by Physicians who Treat Insomnia (US)

It is difficult to imagine why taking Singulair would increase the risk that someone would complete suicide.  After all, what does a leukotriene receptor antagonist have to do with mental health?  I don't know. But doctors, ask yourself, have you ever had a Singulair patient stop taking it...

The FDA’s approval of Abilify for treatment of acute manic and mixed episodes of pediatric Bipolar Disorder is a very important milestone.   Treatment with Abilify already has had growing off-label use in the pediatric population, in both acute and chronic settings, because of its favorable...

Triple-reuptake inhibitors (TRIs) represent an emerging class of antidepressant drugs in development with potential application for other disorders including ADHD and obesity.   By potentiating all three of the main monoamine neurotransmitters implicated in depression  - serotonin, norepinephrine,...

Fluovoxamine is perhaps the last participant in the SSRI explosion of the 1980's.  It is also the least used and hence, least profitable entry in the SSRI horse race, primarily because of timing rather than any particular pharmacological deficiency.  To believe that this attempt to rejuvenate...

Fluvoxamine, the least known of the selective serotonin reuptake inhibitors in the US, will now have an FDA approved controlled release version - Luvox CR - for the treatment of OCD and Social Anxiety Disorder.   The collaboration between Jazz Pharmaceuticals and Solvay will have only an uphill...

Deep brain stimulation (DBS), an FDA approved device treatment for Parkinson’s Disease and essential tremor, has demonstrated quite remarkable findings in several very small pilot studies for treatment resistant depression.   There is great hope among the device makers – namely Medtronics...

Smoking cigarettes is a serious health problem throughout the world and smoking cessation is an important clinical problem.  Stopping smoking is tremendously difficult for some because of the highly addictive nature of nicotine, but also because of the predominant use of smoking as a form of self-medication...

I believe publications such as these are probably useful reactions to over-prescribing antidepressants for anything that ails you (which is what has been occuring until the recent suicide scare in adolescents).  Nevertheless, such generalizations have significant influence even though they are...

The announcement of this small biomarker study for MEM 3454, an alpha-7 neuronal nicotinic receptor (NNR) partial agonist in joint development by Memory Pharmaceuticals and Roche for the treatment of cognitive impairment associated with schizophrenia (CIAS), seems like a step in the right direction...

Based on Lilly's early results, it is too soon to tell if its glutamate medication will achieve clinical utility.