GLG News by Physicians who Treat Insomnia (US)

Extavia, Novartis' brand of  interferon beta 1b, has been approved for the  treatment of multiple sclerosis by the European Union.  With FTY72, Fingolimod, Novartis has the eye on filing NDA by the end of 2009.  While essentially identical to Bayer's Betaferon interferon beta 1b,...

Manipulation of the nicotinic receptor is a novel way to treat ADHD which has significant potential to modify the symptoms of this disorder and to enhance learning and memory.  We have had some difficulty with side effects of varenicline which is a nicotinic partial agonist used in smoking cessation...

The data on ABT-089 in adults has been released with positive results, whereas the adolescent/childhood trial is on-going for this novel compound for ADHD.  The key difference is the potential to improve learning, not simply regain attention and lessen hyperactivity.

Percutaneous coronary interventions are standard therapy for both acute MI patients as well as unstable coronary syndromes, and are commonly utilized as preventive therapy in some patients. The practice of thrombectomy prior to stenting in these patients is simple and fairly risk-free, but...

I am a heavy user of ARB's and Tekturna.  This article does not really show anything of significance.  Most practicing physicians have seen much better results and much better tolerability with ARB's than diuretics. I do not think this is going to change prescribing habits of anyone. ...

It’s not clear just how BrainCells’ BCI-540 works but the company claims the drug acts by way of promoting neurogenesis without an effect on serotonin neurotransmission.   While SSRI’s also promote neurogenesis, a downstream effect believed to favorably impact mood and anxiety, they obviously...

 Study will be ridiculed.   1) Comparator drug is not appropriate. 2) Not an outcomes study. 3) Time frame too short to be clinically significant. 4) Drug too expensive for first line use. 5) Long term safety not established.

This article serves as a reminder that it is institutional, not individual diversion of controlled substances that is the principal basis of this important public health concern.

Vicodin is used mostly widely used pain medication because it can be prescribed over the phone without a written prescription. That said, familiarity with this compound will make it an easy sell to physicians. Cost will prove the main barrier to widespread adoption- will compete against generic morphine...

Don't bother listening to the May 6 audio presentation, as it is a useless waste of time.  Just look at the pdf slide presentation, showing tapentadol IR to provide equivalent pain control to 10 or 15mg oxycodone, with reduced GI side effects, in treating acute bunionectomy pain and also arthritis...