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GLG News by Physicians who Treat Hypertension (US)

Carlos Dujovne, MD, Professor of Medicine and Director
Carlos Dujovne, MD, Professor of Medicine and Director
OREGON HEALTH & SCIENCE UNIVERSITY - CC
Analysis of: No right to experimental drugs for dying patients: Supreme Court (news.yahoo.com)
One, twenty years ago I was the chairman of the government affairs committee of the American Society for Clinical Pharmacology and Therapeutics; under that role my committee was successful lobbying for approval new investigational drugs for possible treatment of AIDS. We were successful in getting the...
Analysis of: New therapy for old woes, Blue Cross measure aims to slow runaway costs, improve quality of healthcare (www.boston.com)
A new idea - I don't think so Trust Blue Cross??????
Analysis of: First Head to Head Study Comparing CRESTOR(TM) and LIPITOR(R) Effects on the Treatment of Atherosclerosis (www.pipelinereview.com)
The announcement the new trial comparing Lipitor to Crestor  is interesting but not unexpected.  It is timed to end near the end of lipitor's patent. A win- which is likely- will certainly help AZN sell their drug against the much cheaper generic lipitor.
Analysis of: First Head to Head Study Comparing CRESTOR(TM) and LIPITOR(R) Effects on the Treatment of Atherosclerosis (www.pipelinereview.com)
Lipitor is the dominant statin on the market and has an indication for reducing the risk of heart attack and stroke. Crestor is more potent than Lipitor, but, because it was approved later, has less data to show for and no indication for lowering the risk of clinical events. Moreover, Zocor (Simvastatin)...
Analysis of: CV Therapeutics' Anti-Ischemic Agent Ranexa(R) Significantly Reduces HbA1c and Other Markers of Diabetes in MERLIN TIMI-36 (www.pipelinereview.com)
Impressive data on Ranexa in HGBA1c. The result of a decrease of 0.64 vs baseline and 0.43 vs placebo are at first glance underwhelming.  But a closer looks shows that the results are realy quite impressive
January 18, 2008
I couldn't agree more
Analysis of: WellPoint patients to review doctors online (www.healthcarefinancenews.com)
Insurance company data is primitive and flawed. Any entity that can manage this data well in the future will be extremely profitable.
Dan Streja, MD, Clinical Professor of Medicine
University of California, Los Angeles
Analysis of: No right to experimental drugs for dying patients: Supreme Court (news.yahoo.com)
The Supreme Court has rejected the use of experimental drugs by the dying patients on the grounds that "The framers (of the US constitution) understood that the pursuit of life is an inalienable right that should not be abridged without due process of law." Over the years our patients with terminal...
Analysis of: Nitromed Halts Marketing of Drug (online.wsj.com)
Apparently doctors aren't quite as easily manipulated by pharma as we all thought.  Despite a vigorous marketing effort, Bidil was seen by cardiologist as what it is- an expensive combination of two generics and was not used- even after insurance companies started to pay for it.
Carlos Dujovne, MD, Professor of Medicine and Director
Carlos Dujovne, MD, Professor of Medicine and Director
OREGON HEALTH & SCIENCE UNIVERSITY - CC
Analysis of: Merck & Co.: Engaging in Risky Business? (www.pharmaweek.com)
My expertise in the clinical research of Torcetrapib and reports presented at the latest American College of Cardiology meetings made me conclude that the failure of  Torcetrapib in rendering clinical benefits were related to intrinsic problems of the drug which effected the nature of the HDL which...
Carlos Dujovne, MD, Professor of Medicine and Director
Carlos Dujovne, MD, Professor of Medicine and Director
OREGON HEALTH & SCIENCE UNIVERSITY - CC
Analysis of: Merck & Co.: Engaging in Risky Business? (www.pharmaweek.com)
Those like myself who have more extensive knowledge on the rational used by the FDA to reject the approval of Rimonabant and know the differences between Rimonabant and Taranabant do not believe that there is an error in judgment by Merck in developing their new cannabinoid receptor antagonist. This...

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