The Expertise Imperative and Compliance Technology
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1. CVD is a major diabetes complication. 2. Recent studies have questioned whether some diabetes drugs increase rather than decrease CVD. 3. The new FDA guidelines place a high burden on the pharmaceutical industry for developing new diabetes drugs without demonstrable CVD risk.
The results of this observational study suggested Lipitor was more effective than simvastatin. This is not terribly surprising. Lipitor is the more potent statin, even allowing for dosing differences. Observational studies, however, have inherent weaknesses in that...
This is an interesting analysis that may be scientifically flawed (because it was based on observational data that is subject to selection, medication compliance and comorbidity biases). It may encourage some prescribers to use Lipitor rather than simvastatin. However, that propensity may continue to...
This analysis of a completed trial suggests that patients using statins plus ezetimibe to achieve an LDL of under 70, had better regression of atherosclerosis than patients with an LDL target of under 100. In addition, the ezetimibe plus statin group did just as well as a group that used statins alone...
The article indicates that medications will be designed to be effective for particular populations. This will prevent the need to try medications which are effective for 50% of the population or less.
1:Crestor is the most potent statin in the market,yet is 3d in sales behind Zocor and Lipitor.2:The efficacy supriority together with its capacity to lower CRP levels led to the highest rate of ASCVD prevention in the shortest period of time evr documented in statin trials.3:The trial in near 18,000...
C. difficile is only linked to antibiotic use about half the time. In addition c. difficile can complicate IBS more that previously thought. This may be why antibiotics that cover c. difficile have been useful in treating irritable bowel syndrome.