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GLG News by Physicians who Treat Acne (US)

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September 5, 2007
It's better to be paid something than nothing
Analysis of: Doctors Offering No-Interest Loans to Patients | www.nytimes.com
Author: GLG Expert Contributor
Financing of health care by physicians is a relatively new phenomenon.   While this practice is most aggressively being used in the arena of non-covered services (plastic surgery, Lasik, etc), it has some relevance to general medicine as well. In the covered services arena, it's pretty simple...
September 5, 2007
Simple, straightforward, and possibly clinically useful.
Analysis of: YM BioSciences USA Cleared By US FDA To Initiate Phase II Clinical Trial Of Nimotuzumab In Children With Inoperable, Recurrent Brain Cancer | www.medicalnewstoday.com
Author: GLG Expert Contributor
Nimotuzumab is a humanized monoclonal antibody against EGFR. Initial results showed some response in patients with GBM and recurrent pediatric gliomas (ASCO 2007).  High grade gliomas have many genetic aberrations including amplification of EGFR, loss of the tumor-suppressor protein PTEN, overexpression...
September 5, 2007
Great technology, but there is competition
Analysis of: Varian Medical Systems Receives FDA 510(k) Clearance for Smart Segmentation™ Tool That Dramatically Speeds Up Radiotherapy Treatment Planning | varian.mediaroom.com
Author: GLG Expert Contributor
Varian's new Smart Segmentation Tool is an addition to their Eclipse planning system which aims to shorten planning time in intesity modulated radiation therapy (IMRT) cases.    Typically, IMRT cases require the planning physician to spend several hourse identifying target structures...
September 5, 2007
Topical treatment for metastatic disease....not likely
Analysis of: Advanced Life Sciences Announces ALS-357 Granted FDA Orphan Drug Designation for Metastatic Melanoma | www.pipelinereview.com
Author: GLG Expert Contributor
ALS-357 has shown pre-clinical success both in-vitro and in-vivo, and is now slated for phase I/II trials. Unfotunately this drug is targeting metastitic melanoma using a topical delivery vehicle.   While this has worked in a mouse, I'm not sure this will really work effectively in humans...
August 30, 2007
Where's the data??
Analysis of: Brain cancer therapy.(Therapeutic vaccine) | www.therapeuticsdaily.com
Author: GLG Expert Contributor
Vaccines are an interesting concept in cancer therapeutics.   However, other than Guardasil, which prevents HPV infection and subsequent risk of cervical cancer, NO other vaccine has shown a true benefit in patients with active cancers.   Look at all the data in melanoma, which has...
August 30, 2007
New breast radiation fractionation not standard
Analysis of: Study Supports Simultaneous Technique for Breast-Conserving Radiotherapy | www.medscape.com
Author: GLG Expert Contributor
Standard breast conserving therapy consists of breast conserving surgery followed by whole breast radiotherapy (to a dose of 45-50.4Gy), followed by a boost to the lumpectomy site of 10-16Gy for a total dose of 61-66Gy.    The boost is typically done after the completion of whole breast...
August 28, 2007
This coud ne a Panora's Box
Analysis of: New Medicare Regulations Adopted To Reduce Certain Hospital Infections And Medical Errors | www.medicalnewstoday.com
Author: Michael Bain, Plastic and Reconstructive Physician, Michael A Bain, MD
If a patient gets a bedsore, who pays for it? Most importantly, what does this mean to KCI and the other wound companies? Where will it end?
August 27, 2007
CMS policies - Not what the doctor ordered
Analysis of: New Medicare Regulations Adopted To Reduce Certain Hospital Infections And Medical Errors | www.medicalnewstoday.com
Author: GLG Expert Contributor
CMS's latests decision to not reimburse hospitals for medical errors and hospital acquired infections has been widely discussed on these newsgroups.   Simpy put, while medical errors and infections are unfortunate and can have adverse consequences, the key here is which of these events could...
August 23, 2007
ASA404 - interesting results
Analysis of: Antisoma's ASA404 1800 mg/m2 lung cancer trial will report positive survival data | www.therapeuticsdaily.com
Author: GLG Expert Contributor
ASA404 is a small-molecule vascular disrupting agent that selectively disrupts established tumour blood vessels, in theory allowing chemotherapy to reach tumor cells. The data to date in NSCLC is quite promising, with significant increases in overall and medial survival when combined with...
August 22, 2007
Speech Recognition Software Improves Efficiency
Analysis of: Philips SpeechMagic Used In Largest Deployment Of Front-End Radiology Speech Recognition In The UK | www.medicalnewstoday.com
Author: GLG Expert Contributor
In the modern era of medicine, where documentation and communication is important, fast turn around of dictated reports (radiology, consultation, progress notes) is important for an efficient workflow. Speech recognition software has improved dramatically over the last decade, allowing for relatively...

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