GLG News by Physicians who Treat ADHD (US)

Good drug with rapid onset.  ? if will create some confusion with adult dosing    

Extavia, Novartis' brand of  interferon beta 1b, has been approved for the  treatment of multiple sclerosis by the European Union.  With FTY72, Fingolimod, Novartis has the eye on filing NDA by the end of 2009.  While essentially identical to Bayer's Betaferon interferon beta 1b,...

Manipulation of the nicotinic receptor is a novel way to treat ADHD which has significant potential to modify the symptoms of this disorder and to enhance learning and memory.  We have had some difficulty with side effects of varenicline which is a nicotinic partial agonist used in smoking cessation...

-Glaxo's pre-pandemic flu vaccine is a double opportunity - a chance to contract now with multiple governments to supply a pre-pandemic vaccine as well as a natural segue to become their future supplier of actual pandemic flu vaccine (when developed).  -When pandemic flu hits, the race will be...

There have been great advances made over the past 40 years in cardiovascular risk assessment.  Nevertheless, 600 people die each day of sudden death. The majority of these individuals had conditions that could have been treated and corrected.

The data on ABT-089 in adults has been released with positive results, whereas the adolescent/childhood trial is on-going for this novel compound for ADHD.  The key difference is the potential to improve learning, not simply regain attention and lessen hyperactivity.

I think the long affect of Aliskiren (3-4 days ) after the last pill is both a benefit and a risk; it is good in the setting on noncompliance but quite a challenge  when  trying to reverse  the hypotensive effects in  emergency situation. It is interesting that it is more effective...

Direct comparisons between potential competing agents often do not exist Initial FDA approval is usually based on comparisons to placebo A new approval does necessarily mean that the new agent is better than existing ones, although this is implied by industry Industry bears all the costs of efficacy...

It’s not clear just how BrainCells’ BCI-540 works but the company claims the drug acts by way of promoting neurogenesis without an effect on serotonin neurotransmission.   While SSRI’s also promote neurogenesis, a downstream effect believed to favorably impact mood and anxiety, they obviously...

Glaxo's new pandemic flu vaccine was just approved for sale and use in the EU.  It has or is trying to establish contracts with multiple countries to supply stockpiles with values in the 100's of millions