Analysis of:
Market Report -- In Play (OCCX) (news.moneycentral.msn.com)
Laser eye-treatment company TLC Vision Corp. said it agreed to sell all the common shares of OccuLogix Inc. to JEGC OCC Corp which is owned by a private equity firm. Occulogix has some emerging therapies in different areas of eye care including Age Related Macular Degeneration and Glaucoma. ...
Analysis of:
CDC warns about contact lens solution (news.yahoo.com)
This article reports a contact lens associated infection with Advanced Medical Optics contact lens solution. Despite owning less than 10% of the Market Share, AMO Complete® MoisturePlus™ (AMOCMP) multipurpose cleaning solution has been implicated in 60% of the cases of Acanthamoeba...
Analysis of:
CDC warns about contact lens solution (news.yahoo.com)
No, this is an entirely different outbreak. The formulation is clearly at fault. The problem is not isolated with Complete Moisture Plus.
Analysis of:
Vegf Trap-Eye Phase 2 Wet Amd Results Reported At Arvo Annual Meeting (www.pipelinereview.com)
The VEGF Trap from Regeneron is a protein made up off human VEGF receptors fused to human immunoglobulin. This compound binds VEGF, preventing VEGF from binding to its natural receptors, interrupting the angiogenic cascade. The phase II study presented at 2007 ARVO showed promising results in patients...
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Ranibizumab, PDT combination successfully treats neovascular AMD (www.osnsupersite.com)
At the recent ARVO meeting, Italian researchers performing a randomized clinical trial on patients with wet AMD found that patients treated with photodynamic therapy (PDT) with Visudyne (verteporfin, Novartis) plus Lucentis(ranibizumab, Genentech) had a better visual result than patients treated with...
Analysis of:
Fish and Vitamin D Linked to Lower Risk of Macular Degeneration (www.medpagetoday.com)
This dietary case control study showed that higher dietary levels of omega-3 fatty acids, mainly from fatty fish, reduced the risk of age-related macular degeneration by 39%. This is very exciting and supports previous obersvational studies showing the protective effects of diet heavy in fish...
Analysis of:
Ranibizumab, PDT combination successfully treats neovascular AMD (www.osnsupersite.com)
This study from Italy shows that PDT combined with monthly Lucentis is much more beneficial compared to PDT alone. Does this data show a role for PDT in the current anti-Vegf era and allow Novartis to still a claim share in this market?
Analysis of:
Vegf Trap-Eye Phase 2 Wet Amd Results Reported At Arvo Annual Meeting (www.pipelinereview.com)
The treatment of "wet" Age-related macular degeneration is a billion dollar market. There has been much excitement regarding the management of of "wet" AMD centered on inhibiting vascular endothelial growth factor (VEGF). Over the past three years, there have been many inhibitors of VEGF...
Analysis of:
Possible Seasonal Link to Uveitis (www.medscape.com)
This study reports that uveitis cases peak in the spring time alleging a link a between springtime allergies and uveitic flare up and episodes. If allergies indeed play a role, it may suggest a common mechanism on uveitic episodes and spur novel treatment modalities to manage uveitis in the future....
Analysis of:
Ranibizumab effective for macular edema due to retinal vein occlusions, ophthalmologist says (www.osnsupersite.com)
There are not many effective treatment options for macular edema secondary to retinal vein occlusions. This pilot study shows that Lucentis can be effective to improve vision and decrease swelling in retinal vein occlusions; and could be another indication for Lucentis.