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GLG News by Pharmacists (US)

Analysis of: Temozolomide And Thalidomide Combination Effective Against Malignant Melanoma Spread To CNS And White Blood Cell Count May Be Prognostic (www.medicalnewstoday.com)
1.  The phase II clinical trial  of the combination thherapy of ( temozolomide and Thalidomide for Malignant Melanoma is very encourganing. It may open new avenue to treat   malignant melanoma  affecting Brain. 2. This  article is important for use  of combination...
Analysis of: Drug Makers’ Push Leads to Cancer Vaccines’ Fast Rise (www.nytimes.com)
1.  Merck and GSK are pushing too much for Cerival cancer vaccine advertisement. 2.  Merck ( Gardasil), and GSK( cervarix) are very tiny age applications, but real disease start after 20, so early vaccination is no use, but Pap smear is more helpful 3. So drug marker push to cancer vaccine lead...
Analysis of: Heart Stents No Better Than Drugs for Chest Pain Over Time (www.bloomberg.com)
Because equivalent results were shown, there will be no change in stent placement volumes.
Analysis of: Biovest Reports Results for Patients Treated with Anti-Cancer Vaccine: BiovaxID(R) Demonstrates Clinically and Statistically Significant Improvement of Disease-Free Survival in Non-Hodgkin's Lymphoma in Pivotal Phase 3 Clinical Trial (biz.yahoo.com)
1. BiovaxID®  is a personalized, patient-specific therapeutic vaccine designed to stimulate the patient's own immune system to recognize and destroy cancerous B-cells that may remain in the body or may arise after the patient has been treated with chemotherapy. 2. Unlike many other approaches...
Analysis of: FDA Alert: Hemorrhagic or Necrotizing Pancreatitis in Patients Taking Byetta (www.fda.gov)
 1. As Byetta is not monotherapy and the clinical trial results  are  not clear about the condition od trial patient, so future of Byetta is  blink
Analysis of: Recent Popular New Reports About Senator Ted Kennedy's Brain Tumor (www.cnn.com)
1.  Public awareness and budget for research for brain will increase. 2. Federal      funding  should increase for GBM ( Glioblastoma multiforme) 3. More researchers will join in this field
Analysis of: UCLA And Biotech Company Develop First Blood Test To Measure Key Hormone That Regulates Iron (www.medicalnewstoday.com)
 Hepcidin the principal iron-regulatory hormone that has been very difficult to measure but earlier it was measured indirect way ( basically   measure the iron binding protein transferrin and ferritin). To overcome this difficulty UCLA group developed new procedure to  measure...
Analysis of: Lilly Diabetes Drug Shows a Life-Extending Promise (www.nytimes.com)
1. The efficacy is not not know about life exdending ( may be the results are coming from heakthy person), so it is not clear. 2. Patient taking injection 2 times is not feasible for long run basis. 3. It  is not monotherapy.
Analysis of: UK Says Kidney Cancer Drugs Are Too Pricey (www.pharmalot.com)
1. Kidney cancer drugs have the potential to extend progression-free survival by five to six months, but at a cost of $40,000 to $70,000 per patient per year.  2. The cost per quality adjusted life year (QALY) gained of these treatments is between $57,000 and $180,000 per patient - based on...
Analysis of: Researchers Look to Pill, Taken Daily, to Avert H.I.V. (www.nytimes.com)
The use of prophylactic drugs for HIV while nominally appealing is fraught with potential dangers that require in-depth research.  With mul-tiple strains of the virus is there any drug that can give complete protec- tion?  Will the impression of protection stimulate reckless behavior that...

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