GLG News by Pediatricians who Treat RSV

Epilepsy patients who have already failed to achieve control on two or three different regimens (be they single or multiple drug regimens) are unlikely to find success with any new regimen -- that's just the nature of the disease, unfortunately.  Failure on seizure medications is more a prognostic...

-Menactra recently gained approval for children 2-10 years old -Unless the ACIP changes its recommended age for routine use (currently 11), this will have little impact -Most children will only need this in this expanded age range for travel to some parts of the world.

The United States Veterans Administration is probably the best HMO in the country, provided you are measuring the attainment of good clinical outcomes at reasonable cost.  Believe it or not, the VA, which has the unenviable task of providing healthcare to a relatively sick and historically disenfranchised...

From the standpoint of what is clinically practical, Avamys is not a new drug: it is fluticasone in a nasal spray, available for years as Flonase, now off patent and available in the U.S. generically and as Veramyst (the same product as Avamys). Despite claims that Avamys/Veramyst is the first drug...

Certainly Zingo has the potential to be used in adults, and falls into the category of old, safe drugs with new, clever formulations. But how necessary is this drug in adult practice? It appears to me that there is often confusion between the pain caused by venipuncture and the anxiety and phobia that...

This is a well written article of an impressive study. Despite small sample size, there was a clear dose response that achieved statistical significance witha  VERY robust LDL reduction in paitents already on maximal conventional lipid lowering agents. This paves the way to larger and longer term...

ISIS 301012 is an important agent in the armenentarium to treat an unmet group of patients with refractory hypercholesterolemia or familial hypercholesterolemia. With outcome directly proportional to amount of LDL lowered, it is important to not just control LDL, but also lower it to aceptable...

-Avastin has been repackaged by some compounding pharmacies in place of Lucentis for an indication for which Avastin is not approved.  They are both Genentech drugs, but with Lucentis being much more expensive.  -This is a bit like grinding up amoxicillin tablets, making them into a suspension,...

Flibanserin is, at its root, a molecule with antidepressant activity.  Decreased libido is, at its root, a cardinal symptom of depression.  So the notion that an antidepressant drug might increase the sexual desire in those who have lost it is not so far-fetched, and pre-clinical trials in...

Fluorosis may occur from hidden sources.  It may be reduced by using mineral free water to mix with powdered formula or solely breast feeding.  Fluorosis can cause a permanent staining of the secondary teeth.