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GLG News by Pediatricians who Treat RSV (US)

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December 1, 2008
Financial analysis of the Gardasil-for-Guys question
Analysis of: Gardasil, Merck's Cervical Cancer Vaccine, Demonstrated Efficacy in Preventing HPV-Related Disease in Males in Phase III Study | www.fiercebiotech.com
Author: GLG Expert Contributor
Everyone who expects Gardasil to be approved for general use in males may be very surprised.  Yes, Gardasil prevents HPV in males, but the cost/benefit ratio is completely off compared to women.  The cost is MUCH higher per case of invasive HPV prevented and the benefit is much lower for penile...
November 18, 2008
Gardasil for selected men only
Analysis of: Gardasil, Merck's Cervical Cancer Vaccine, Demonstrated Efficacy in Preventing HPV-Related Disease in Males in Phase III Study | www.fiercebiotech.com
Author: GLG Expert Contributor
-Gardasil has been shown effective in men to prevent infection with high-risk HPV subtypes.  This is great news for some men. -Gardasil when given to all women (now currently in roll-out) will interrupt heterosexual HPV transmission.  Sexually active gay/bisexual males will benefit...
November 10, 2008
ER testing for HIV: does anyone else see a problem with this?
Analysis of: Rapid HIV Testing in the ER Boosts Diagnoses, Screening | www.medcompare.com
Author: GLG Expert Contributor
-I'm thrilled to see that a provider evaluating someone for an STD also tests for HIV -but- -I'm appalled that people can be seen in an ER for a suspected STD, just like I would be for those that go for colds and ear infections.  How much did each of those chlamydia and gonorrhea and syphilis...
November 4, 2008
Your doctor doesn't get a flu shot WHY????
Analysis of: Flu shots a tough sell to health care workers | ap.google.com
Author: GLG Expert Contributor
-A recent informal survey found that many docs and nurses (60% of healthcare workers overall) don't get an annual flu vaccine, despite proven efficacy, easy availability at their place of work, and risk of contagion to patients and colleagues.  -This puts some of the most...
November 3, 2008
Parental "choice" against flu vaccine would be unwise
Analysis of: Flu Vaccine for Preschoolers | www.nytimes.com
Author: GLG Expert Contributor
-Parents in NJ are fighting a new state mandate requiring influenza vaccine in preschoolers -Allowing an override of this mandate would be dangerous but parents will have only themselves to blame if their unvaccinated kids get sick
November 3, 2008
Rotavirus vaccine delivers
Analysis of: Vaccine Slashes Diarrheal Ilness in Kids | www.nytimes.com
Author: GLG Expert Contributor
Rotateq is a great vaccine - it protects both vaccinated patients and also gives some protection to their not-yet-vaccinated peers Although in the US it is rare to die from rotavirus illness, the economic savings on lost school/work days and decreased hospital admissions and ER visits is huge.
November 3, 2008
Stockpiling flu vaccines at home will never make sense given Americans' sensibilities
Analysis of: U.S. looks at whether home drug stockpiles for flu pandemic makes sense | canadianpress.google.com
Author: GLG Expert Contributor
Most American families are not familiar with signs and symptoms of influenza.  Asking them to use (and not use) a home supply of antivirals would be insanity, stretching thin the amount of antivirals available and depriving them to those in true need.  To ask them to use these meds appropriately...
October 13, 2008
When Your Neighbor Takes an Antibiotic, So Do You
Analysis of: C. Difficile And Antibiotics Not Necessarily Linked, Study Finds | www.sciencedaily.com
Author: GLG Expert Contributor
This study did not conclude that antibiotic use does not precipitate C. difficile infections.  What it found was that the individuals who are infected with C. diff did not necessarily take antibiotics in the six weeks preceding their infection.  In my mind, rather than demonstrating that C....
October 6, 2008
cold medications overdose- med fault or Dr. fault?
Analysis of: FDA urged to recall cold medicines for youngsters | news.yahoo.com
Author: GLG Expert Contributor
There is a alot of information in the media  about the dangers of givng OTC cough medication to young children . Many children have ended up in the emergency room after "over-ingesting" "cold remedy products that include OTC antihistamines, decongestants and  cough suppressants. Also when...
September 29, 2008
Published Evidence Bias: Approved Drugs Are Just the Tip of the Iceberg
Analysis of: Many Trial Reports on FDA-Approved Drugs Go Unpublished | www.washingtonpost.com
Author: GLG Expert Contributor
This study looked at drugs that were eventually approved by the FDA, and found that only 43% of early phase (non-"pivotal") trials were published in the medical literature.  But imagine what this means for drugs that ultimately fail: if drugs that are destined for success are withholding 57% of...

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