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GLG News by Pancreatic Cancer Oncologists in the U.S.

Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
August 9, 2007
ERBITUX
Analysis of: Bristol-Myers Squibb and Imclone Systems Significantly Expand ERBITUX Clinical Development Program (www.pipelinereview.com)
The comprehensive clinical program will supplement the significant body of clinical data existing for ERBITUX in colorectal and head and neck cancers by exploring the use of ERBITUX in additional tumor types including brain, breast, bladder, gastric, lung, pancreas and prostate
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
August 9, 2007
ERBITUX
Analysis of: Bristol-Myers Squibb and Imclone Systems Significantly Expand ERBITUX Clinical Development Program (www.pipelinereview.com)
The coverage restrictions placed on the FDA-approved indication have no scientific basis and are incompatible with good clinical practice," said Roger M. Perlmutter, M.D., Ph.D., executive vice president of Global Research and Development at Amgen. "We are concerned that inappropriately limiting coverage...
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
August 6, 2007
ESA
Analysis of: Amgen Responds to Final CMS National Coverage Determination on Use of Erythropoiesis-Stimulating Agents in Oncology (www.pipelinereview.com)
My understading id medicare need to cover all FDA indicated drugs. Here CMS violating FDA indication for Aranesp and procrit
Taral Patel, MD, Oncologist
Taral Patel, MD, Oncologist
Mid Ohio Oncology Hematology Inc.
August 3, 2007
Growth factor use
Analysis of: Amgen Responds to Final CMS National Coverage Determination on Use of Erythropoiesis-Stimulating Agents in Oncology (www.pipelinereview.com)
Decrease use by 20-25% use of ESA. This may lead discounting and higher rebate from both amgen and orto-biotech to sustain market share. Since most of amgen contract with aranesp and neulasta use. It may effect use of neulasta. Next 6 month CMS may restrict use of Neulasta and neupogen for neutropenia...
Donald Fleming, MD, Division Head of Hematology and Oncology
Donald Fleming, MD, Division Head of Hematology and Oncology
Davis Health System, Inc.
Analysis of: Coley Pharmaceutical Group's Vaccine Adjuvant, VaxImmune, to Enter Phase III Clinical Testing as Part of GlaxoSmithKline's Novel Cancer Immunotherapeutic in Non-Small Cell Lung Cancer (www.pipelinereview.com)
Vaccine therpy has been of great interest in fight against cancer Vaccine therapy is likely to impact on natural history of cancer?
Donald Fleming, MD, Division Head of Hematology and Oncology
Donald Fleming, MD, Division Head of Hematology and Oncology
Davis Health System, Inc.
Analysis of: FDA Approves Wyeth's Torisel For Treatment Of Advanced Kidney Cancer (www.medicalnewstoday.com)
The mTOR class of drugs are going to be a success for renal cell cancer The mTOR drugs are likely to have broad appeal
Donald Fleming, MD, Division Head of Hematology and Oncology
Donald Fleming, MD, Division Head of Hematology and Oncology
Davis Health System, Inc.
Analysis of: Hospital-borne ailments face Medicare budget ax (www.indystar.com)
CMS has ecome very aggressive about denying coverage of so called negative impact therapy What is the real motive behind the CMS debate and various therapies? Cancer care has seen this time and time again.
Donald Fleming, MD, Division Head of Hematology and Oncology
Donald Fleming, MD, Division Head of Hematology and Oncology
Davis Health System, Inc.
Analysis of: Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma (bloodjournal.hematologylibrary.org)
zanolimumab (HuMax-CD4) will contribute significantly to CTCL therapy zanolimumab (HuMax-CD4) has much potential in the market share
Donald Fleming, MD, Division Head of Hematology and Oncology
Donald Fleming, MD, Division Head of Hematology and Oncology
Davis Health System, Inc.
Analysis of: GlaxoSmithKline Announces Swiss Approval Of Tyverb®, A New Oral Treatment For Advanced Breast Cancer (www.medicalnewstoday.com)
Is Lapatinib a major accomplishment for GSK? Was the recent phase III that led to approval understood? Are there threats to Lapatinib in the near furure?
Analysis of: Volatility Becomes Symptom (online.wsj.com)
The ASCO abstract WSJ article claims that meaningful information is available to some but not everyone simultaneously.  ASCO defends it policy by wishing to serve it's members at the potential expense of any other group.  Despite this uneven distribution of information, traders still seem...

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