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GLG News by Ophthalmologists

Analysis of: Hormone therapy and age-related macular degeneration: the Women's Health Initiative Sight Exam Study. (archopht.ama-assn.org)
This study demonstrates that many labs are working on finding other new methods to treat earlier forms of macular degeneration before it progresses to the wet form.  The use of hormone replacement, already a common practice since years, may also show to be useful for management of macular dege...
Analysis of: Intravitreal triamcinolone for refractory diabetic macular edema: two-year results of a double-masked, placebo-controlled, randomized clinical trial. (www.ncbi.nlm.nih.gov)
This study shows that other NON-anti VGEF medicines continue to have a role in treating macular swelling and will not likely be completely abandoned in favor of the more expensive options now available.  Given its likely affectivity as an adjunct or possible replacement for many patients, and its...
Sanjay Rao, MD, Medical Director
Sanjay Rao, MD, Medical Director
Lakeside Eye Clinic
Analysis of: Better PK results forseen with custom overlapping incision shapes (www.ophthalmologytimes.com)
This article describes early experience with Intralase enabled keratoplasty.  Conventional keratoplasty, or corneal transplantation, is performed using specialized blades called trephines.  These blades are limited in that they can produce only a single type of cut.  Intralase enabled...
Analysis of: Another Contact-Lens Solution Recalled (www.newsinferno.com)
While Benzalkonium Chloride (BAK) is the most common eye drop preservative (85% of all drops) it has an adverse effect on the ocular surface.  With prolonged use i.e. dry eyes and glaucoma preservative toxicity because a serious problem.  Currently uni-dose artificial tears are available but...
Vincent de Luise, MD, Head of Cornea Service
Vincent de Luise, MD, Head of Cornea Service
Opticare Eye Health Center P.C.
Analysis of: Pfizer to Cut Its U.S. Sales Force by 20% (www.nytimes.com)
What is the effect of downsizing sales representatives on drug sales for Pfizer?  
Gaurav Shah, MD, Associate Professor of Ophthalmology
Gaurav Shah, MD, Associate Professor of Ophthalmology
Washington University Medical Center
November 20, 2006
Laser to drusen trial
Analysis of: Laser Treatment Ineffective In Preventing Vision Loss In Early Age-Related Macular Degeneration (www.pharma-lexicon.com)
It is not surprising that laser therapy is not effective for patients with macular degeneration. Initially there was a significant interest in this therapy, but as this well designed trial has shown us that thermal treatment is not the answer for dry ARMD. AREDS I and AREDS II are now the most important...
November 17, 2006
AMD Prevention
Analysis of: Laser Treatment Ineffective In Preventing Vision Loss In Early Age-Related Macular Degeneration (www.pharma-lexicon.com)
Prevention of disease progression remains an important goal for patients with early AMD.  This high quality study, the Complications of AMD Prevention Trial, demonstrated no benefit for subjects receiving low intensity laser treatment.  Other trials such as the National Eye Institute's AREDS...
Sanjay Rao, MD, Medical Director
Sanjay Rao, MD, Medical Director
Lakeside Eye Clinic
Analysis of: Multifocal IOL provides high-quality vision for patients (www.ophthalmologytimes.com)
This article describes the experience of 3 European surgeons with the Tecnis multifocal intraocular lens.  Currently, the only two FDA approved multifocal lenses in the U.S. are Alcon's Restor and AMO's Rezoom.  The Tecnis multifocal is unique among current multifocal options in that it incorporates...
Sanjay Rao, MD, Medical Director
Sanjay Rao, MD, Medical Director
Lakeside Eye Clinic
Analysis of: Femtosecond laser technology enhances corneal grafting (www.OSNSuperSite.com)
This article describes how the Intralase laser can be used to perform corneal transplantation.  The Intralase femtosecond laser has traditionally been utilized to create a corneal flap in the LASIK procedure.  This article describes the experience of a team of Italian corneal surgeons utilizing...

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