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GLG News by Ophthalmologists

Analysis of: Fish and Vitamin D Linked to Lower Risk of Macular Degeneration (www.medpagetoday.com)
This dietary case control study showed that higher dietary levels of omega-3 fatty acids, mainly from fatty fish, reduced the risk of age-related macular degeneration by 39%.  This is very exciting and supports previous obersvational studies showing the protective effects of diet heavy in fish...
Analysis of: Ranibizumab, PDT combination successfully treats neovascular AMD (www.osnsupersite.com)
This study from Italy shows that PDT combined with monthly Lucentis is much more beneficial compared to PDT alone.  Does this data show a role for PDT in the current anti-Vegf era and allow Novartis to still a claim share in this market?
Analysis of: Vegf Trap-Eye Phase 2 Wet Amd Results Reported At Arvo Annual Meeting (www.pipelinereview.com)
The treatment of "wet" Age-related macular degeneration is a billion dollar market.  There has been much excitement regarding the management of of "wet" AMD centered on inhibiting vascular endothelial growth factor (VEGF).  Over the past three years, there have been many inhibitors of VEGF...
Analysis of: Possible Seasonal Link to Uveitis (www.medscape.com)
This study reports that uveitis cases peak in the spring time alleging a link a between springtime allergies and uveitic flare up and episodes.  If allergies indeed play a role, it may suggest a common mechanism on uveitic episodes and spur novel treatment modalities to manage uveitis in the future....
Analysis of: Ranibizumab effective for macular edema due to retinal vein occlusions, ophthalmologist says (www.osnsupersite.com)
There are not many effective treatment options for macular edema secondary to retinal vein occlusions.  This pilot study shows that Lucentis can be effective to improve vision and decrease swelling in retinal vein occlusions; and could be another indication for Lucentis.
Analysis of: Phacoemulsification and IOL implantation in older populations could help prevent glaucoma (www.osnsupersite.com)
In this exciting study, they report that phacoemulsification and IOL implantation significantly decreases intraocular pressure in ocular hypertensive eyes in elder patients.  The ocular hypotensive effect may prevent glaucoma and be another option in glaucoma managment.
Analysis of: Novagali Pharma Announces FDA Clearance of IND for US Pivotal Phase III Trial of Nova22007 for Treatment of Dry Eye Syndrome (www.pipelinereview.com)
The current paradigm of Dry Eye disease revolves around inflammation as a key and essential component in its development and progression. Many current and developing regimens (artificial tears, secretagogues such as Ecabet sodium and diquafosol and 15-HETE, mucomimetics such as Milicin, etc...) do...
Analysis of: Toric lens approval unlikely this year, STAAR Surgical says (www.ophthalmologytimes.com)
For a company that has had its share of rejections and problems with the approval of a phakic IOL (ICL Visian)  that it tried to have enter the US market almost a decade ago, things are not improving much for Staar.  The company recently reported that despite its request over one year ago...
Analysis of: Better Vision Without Looking Your Age (www.nytimes.com)
Mutifocal iols are currently used to try to correct distance and near vision.  While patients are often pleased by their improved near vision without glasses, many complain of poor optical quality for distance vision.  Due to great out of pocket costs and poor quality of vision under some...
Analysis of: Statins may reduce the risk of developing cataract, late AMD (www.osnsupersite.com)
Data mining is a career choice for a growing number of academic Ophthalmologists and Optometrists. Rightly so, since newer analyses of well conceived population data bases found in the Blue Mountain or the Framingham cohorts continue to provide valuable epidemiologic information.Burgeoning case loads...

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