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GLG News by Ophthalmologists (US)

Analysis of: Warning over drug trial’s effects on testing (www.ft.com)
This article warns against "taking testing out of the hands of companies" and warns against the idea that a drug is receiving a Phase 3 trial without early phase testing.  The CATT trial certainly marks a huge change in drug development but what the pharma industry is not appreciating...
Analysis of: LASIK Worries? Some May See Better with Alternatives (www.washingtonpost.com)
Although the lask procedure as the primary method of keratorefractive surery has been under scrutiny recently it remains the mainstay of refractive surgery.  With a 95% approval it is difficult to critisize its effectiveness. However the 5% patient complaints must be addressed.  The risk of...
Analysis of: Experts see boost to genetic testing from US bill (www.reuters.com)
The Genetic Information Nondiscrimination Act (GINA), which will soon become law, will protect Americans who choose to have genetic testing against the fear of discrimination by employers and health insurers. The idea of personalized medicine can not become a reality with out the passage of GINA.
Analysis of: LASIK Worries? Some May See Better with Alternatives (www.washingtonpost.com)
The FDA report and scrutiny of LASIK complaints reveals what consientious LASIK surgeons have known for years:  Not everyone who walks through your doors is a good lasik candidate and you should not laser everyone.  About 1 out of 4 patients that consider lasik are actually good candidates...
Mark Packer, MD, Clinical Associate Professor of Ophthalmology
Mark Packer, MD, Clinical Associate Professor of Ophthalmology
OREGON HEALTH & SCIENCE UNIVERSITY - CC
Analysis of: LASIK Worries? Some May See Better with Alternatives (www.washingtonpost.com)
The media reporting on the FDA hearings on LASIK has generally highlighted unhappy patients' stories and the comments of FDA officials and panel members.  However, The Washington Post's Lauran Neergard has written an insightful article that foresees an important future trend in refractive surgery....
Analysis of: New model of mini glaucoma shung significantly lowers IOP (www.osnsupersite.com)
A new model of the increasing popular Ex-Press Shunt is quite effective in an early study.  Its is quite safe and effective; and simpler substitute for trabeculectomy.  It could be the first line  in the surgical management of glaucoma.
Analysis of: Injectable glaucoma drug shown to reduce IOP in clinical study (www.osnsupersite.com)
Alcon (ACL) reported positive interim results for their injectable medication for glaucoma.  A single injection of anecortave acetate  resulted in control of IOP at the three month follow up.  This could be a promising medication for IOP control in glaucoma.
Analysis of: Pilot trial for toric correction with light-adjustable lens yields promising early results (ophthalmologytimes.modernmedicine.com)
The light adjustable lens is a lens implant that is placed in the eye like a tradition intraocular lens during cataract surgery.  The unique difference is that it can be treated with a special light after surgical implant (weeks to months later) to correct any residual refractive errors or to fine...
March 31, 2008
Truth vs. Profits
Analysis of: Comparison of AMD Treatments Trials (CATT): Lucentis — Avastin Trial (www.pipelinereview.com)
In many respects, it is good that this trial was done.  For many years, retinal physicians had used Avastin injections preferentially over Lucentis for the treatment of AMD because of the vast difference in cost.
Analysis of: New Focus of Inquiry Into Bribes: Doctors (www.nytimes.com)
It is a common business practice for companies to wine and dine potential clients in an effort to secure new business contracts.  This is not considered to be a bribe, it is considered good business practice.  Is Stryker's case that different? Physicians go into practice for many reasons. ...

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