GLG News by Nursing Home & Skilled Nursing Facility Experts

Nimotuzumab is a humanized monoclonal antibody against EGFR. Initial results showed some response in patients with GBM and recurrent pediatric gliomas (ASCO 2007).  High grade gliomas have many genetic aberrations including amplification of EGFR, loss of the tumor-suppressor protein PTEN, overexpression...

Varian's new Smart Segmentation Tool is an addition to their Eclipse planning system which aims to shorten planning time in intesity modulated radiation therapy (IMRT) cases.    Typically, IMRT cases require the planning physician to spend several hourse identifying target structures...

ALS-357 has shown pre-clinical success both in-vitro and in-vivo, and is now slated for phase I/II trials. Unfotunately this drug is targeting metastitic melanoma using a topical delivery vehicle.   While this has worked in a mouse, I'm not sure this will really work effectively in humans...

It is important to look closely at the new niche called Concierge Medicine. It is obviously created out of  a special need and will prove lucrative for physicians who choose to go that route. But there are larger questions of access and ethics of exclusivity/ One has to consider whether this...

The recent changes in leadership in the LTAC space is significant and suggests a tightening of operations. It is important to monitor the overall long term space as well as follow who goes where.  The changes are not insignificant, but may not be as ominous as they appear on the surface. Investors...

Vaccines are an interesting concept in cancer therapeutics.   However, other than Guardasil, which prevents HPV infection and subsequent risk of cervical cancer, NO other vaccine has shown a true benefit in patients with active cancers.   Look at all the data in melanoma, which has...

Standard breast conserving therapy consists of breast conserving surgery followed by whole breast radiotherapy (to a dose of 45-50.4Gy), followed by a boost to the lumpectomy site of 10-16Gy for a total dose of 61-66Gy.    The boost is typically done after the completion of whole breast...

With skyrocketing enrollment nubers due to immagration and the "Graying of America", Federal and State Health Care Agencies will be compelled to move patients to managed care.

CMS's latests decision to not reimburse hospitals for medical errors and hospital acquired infections has been widely discussed on these newsgroups.   Simpy put, while medical errors and infections are unfortunate and can have adverse consequences, the key here is which of these events could...

The fact that they are pushing the maximum dose indicates that the Phase I trials went well. The market is waiting for new classes of antpsychotics/schizophrenia agents due to the endo side effects associated with current market leaders.