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GLG News by Non-Electrophysiologist Cardiologists (US)

Analysis of: Microsoft launches Web site to hold medical records (uk.reuters.com)
Medical practice is behind financial serivces in terms of computerization of records. There is no one medical record system(like Microsoft Word) that is used by many practioners.  Inaccessiblity of old medical records leads to increased cost of care because of unnecessary repetition of medical...
Analysis of: Galvus(R) receives European approval as new treatment for type 2 diabetes with broad range of indications (www.pipelinereview.com)
The approval of Galvus in Europe increases the pressure on the FDA to approve its use in the United Status.
September 14, 2007
Generic Coreg
Analysis of: FDA Approves First Generic Versions of Coreg (www.fda.gov)
First of all, the use of carvedilol will significantly increase and potentially can be the number 1 prescribed beta blocker.  Secondly, CHF patients with limited pharmaceutical benefits will now have access to the best beta blocker available for their disease.  Finally, this will negatively...
Analysis of: AstraZeneca and Abbott Announce Selection of Next-Generation Fenofibrate (ABT-335) and Crestor Fixed-Dose Combination (pharmalive.com)
Although the pill would be effective in lowering cholesterol and triglycerides, there is no outcome data yet to show benefit comparable to Lipitor in lowering cardiovascular events. There is a report of an observational study with simvastatin, another lipid lowering drug, which shows 30% REDUCTION in cardiovascular...
Analysis of: AstraZeneca and Abbott Announce Selection of Next-Generation Fenofibrate (ABT-335) and Crestor Fixed-Dose Combination (pharmalive.com)
This article is important because it highlights the potential for a drug that will be well received.  The combination of a statin and a fibrate is often used in clinical practice to achieve target lipid levels and a pill that would combine these two drugs would be very practical.  The only...
September 6, 2007
Competing against AIMHIGH
Analysis of: AstraZeneca and Abbott Announce Selection of Next-Generation Fenofibrate (ABT-335) and Crestor Fixed-Dose Combination (pharmalive.com)
This article is relevant because of the concept of combining statins with other agents is going to become the norm for "next" generation lipid agents. The question is which combo will be doctors prescribe?
September 4, 2007
Ease of use
Analysis of: St. Jude Medical Announces Japanese Approval Of The Angio-Seal STS Plus Vascular Closure Device (www.medicalnewstoday.com)
St. Jude Medical has greatly modified their Angioseal closure device over the years to provide a device that is both efficacious and user friendly.  One of the difficulty with previous versions was the multiple steps, but with the STS platform, they have created a device that provides complete...
Ramin Ebrahimi, MD, Director of Cardiac Catheterization Lab
Wadsworth VA Medical Center
Analysis of: St. Jude Medical Announces Japanese Approval Of The Angio-Seal STS Plus Vascular Closure Device (www.medicalnewstoday.com)
The repositioning of the hole, also present with the VIP version is a mild improvement to decrease sheath manipulation. Otherwise the device has not changed much in the past few years. While a very good device in general, its primary limitaions listed below still remain. 1. not allowing re-access...
Analysis of: New Data Highlights Long Term Tolerability and Sustained Benefits of the Exelon Patch in the Treatment of Alzheimer’s Disease (pharmalive.com)
Exelon is an excellent drug for the stablization of cognitive decline in Alzheimer's disease.  It's use has been limited by its GI side effects. It has a unique mechanism of actioncompared to other drugs on the market. The availabilty of a transdermal deliviery system will permit much broader use...
August 28, 2007
Medical Tourism
Analysis of: American's Gamble for Bargain Surgery Abroad (www.medpagetoday.com)
Medical Tourism is purely linked to lower costs for the same procedure.Most of these relate to 1)Small elective surgeries 2) Non-Urgent Cardiac and Non-Cardiac Procedures and Operations 3)Cosmetic Procedures 4)Dental and Vision corrective procedures 5)Radiologic Procedures(Diagnostic and Ther...

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