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GLG News by Neurologists who Treat Epilepsy (US)

Analysis of: Medtronic Gets Approval for Artificial Neck Disc (www.medscape.com)
-the Prestige disc, and later the Bryan disc, are likely to have much more success than the lumbar discs -The surgical community was eagerly awaiting this approval.  There is significant patient demand for this technology -Medtronic has traditionally had very good success with CMS negotiations,...
Analysis of: Medtronic Neck Disc as Good as Fusion: FDA Staff (www.medscape.com)
-Medtronic is likely to see excellent sales of its cervical disc replacement products -The data on the Bryan disc is strong, and FDA will likely grant approval shortly -Medtronic has come to market with the first FDA approved cervical disc replacement, and the surgical community is eager to incorporate...
Analysis of: UPDATE: Novartis Wins FDA OK For Alzheimer's Drug Patch (money.cnn.com)
Alzheimer's drug patch could change quality of life of the patient and their family. Usually patients with Alzheimer's disease have more than one disease and takes three up to fifteen different medications a day. Long span release patches are very convenient to this patients for many reasons, not only...
Analysis of: Abbott Sued By Drug Reps On Overtime Pay (www.therapeuticsdaily.com)
Drug reps are traditionally not the hardest working of people, although they are given large territories to cover in most areas and spend a great deal of time away from home. The drug companies expect production, via a volume of physician and pharmacy calls and ultimately sales. The reps, in most cases...
Analysis of: New Brain-Imaging Technique Detects Early Stages of MCI, AD (www.medscape.com)
This technology may allow physicians to diagnose brain atrophy and dementia in its early stages, but the specificity of the diagnosis is still unproven.  This shortcoming will make it very difficult to make any advances in treating Alzheimer's based on findings from this imaging...
Analysis of: Shire Receives Approvable Letter From FDA for INTUNIV(TM) (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD (www.therapeuticsdaily.com)
My clinical experience with Tenex (guanfacine) was that it was most effective as an add-on treatment for ADHD with associated aggressive behavior. I expect that Intuniv will have the same efficacy limitations. Nonetheless, Intuniv's ease of use and tolerability along with FDA approval should...
June 18, 2007
Pseudo-EEG testing
Analysis of: Aspect Medical Systems' psych treatment (biotech.seekingalpha.com)
I agree with Dr Martin, but  it should also be noted that the "science" of using EEG to assess response to meds for psychiatric diseases (as opposed to epilepsy) typically uses quantitative and averaging methods, rather than raw data.  The nature of EEG is dynamic and brief  segmental...
Analysis of: Over-The-Counter Weight Loss Drug Approved (abclocal.go.com)
Alli faces many difficulties in the marketplace which will limit sales in the long run and which may lead to litigation and FDA withdrawal.
Analysis of: Pfizer To Launch Antiretroviral Maraviroc In July After FDA Tests Conclude, Official Says (www.medicalnewstoday.com)
Maraviroc will aid decrease HIV drug resistence. Because maraviroc's mechanism of action is different from the other antiretrovirals, its use can help those patients with HIV resistant mutations.
Analysis of: U.S. urges strongest warning on 2 diabetes drugs (www.iht.com)
The recent meta-analysis published in the New England Journal of Medicine suggests an increased risk of myocardial infarction in patients taking rosiglitazone (Avandia).  Additionally, there was an increased risk of death, but it did not reach stastistical significance.  Black-box warnings are...

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