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GLG News by Neurologists (EU)

June 11, 2007
effective treatment?

By a GLG Expert Contributor

Analysis of: Acorda Therapeutics Begins Second Phase 3 Clinical Trial of Fampridine-SR in Multiple Sclerosis (pharmalive.com)

I am not sure that 4-aminopyridine, a long known drug, will efectively improve walking. As important as the walking ability are other clinical features of MS, e.g. ataxia, dementia or bladder dysfunction. This should also be tested.

June 4, 2007
Urgent need for clinical trials in ALS

By a GLG Expert Contributor

Analysis of: Avicena Highlights Key Collaborators in Amyotrophic Lateral Sclerosis (ALS) Dose Escalation Study (pharmalive.com)

There is not much information of the drug ALS-02 in the paper. The term neuroprotection is defined not very well and describes a great number of different molecular mechanisms. The low number of patients will not allow implications for clinical efficacy.

May 21, 2007
Impact on Betaseron sales of early-tyreatment indication

By a GLG Expert Contributor

Analysis of: Bayer's Betaseron found efficacious in multiple sclerosis patients (www.spiritindia.com)

The most recently reported data on Betaseron highlight the usefulness of early treatment of multiple sclerosis (MS) patients. These results allow to widen significantly the number of potential users of Betaseron. They are consistent with the results previously obtained with Avonex, one of...

December 11, 2006
Surgery for herniated lumbar disc

By a GLG Expert Contributor

Analysis of: For Herniated Lumbar Disk, Medical Therapy Matches Surgery (www.medpagetoday.com)

To evaluate further the role of surgery vs. medical treatment.

October 20, 2006
Cervical artificial disc

By a GLG Expert Contributor

Analysis of: F.D.A. Panel Supports Artificial Disks for Upper Spine (www.nytimes.com)

There will be increased public demand for the new devices which are perceived as superior to the traditional way of operating cervical discs.

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