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GLG News by Neonatal-Perinatal Physicians

March 31, 2008
So it begins...
Analysis of: FDA Investigating Possible Link Between Singulair and Suicide (www.foxnews.com)
-Reports of suicidality have been added to Mercks' PI for Singulair -The media have begun to report on this in the past few days and patients are already making calls to their docs -A la Vioxx, Singulair is poised to become the next whipping boy for every depressed asthmatic...
Analysis of: Vaccinating Boys for Girls’ Sake? (www.nytimes.com)
Everyone who thinks that the FDA is going to license a vaccine as costly as Gardasil for boys is insane (sorry if I'm being too subtle). Girls get cervical cancer; the rates of penile and anal cancers from HPV is minuscule in comparison. The cost of Gardasil for girls alone is going to strain a...
Analysis of: Health insurers take a dive on WellPoint's warning (www.marketwatch.com)
Face the facts: In the US, health care costs are, in large part, demand driven. Sure, there is the supply push issue, but very few physicians actually would subject their patients to unnecessary services or procedures--and those who do continue to face censure and exclusion from insurance plans and...
Analysis of: Phase II Clinical Trial of ALN-RSV01 Demonstrates Statistically Significant Anti-Viral Efficacy with an Approximately 40% Reduction in RSV Infection Rate and 95% Increase in Infection-Free Subjects (www.pipelinereview.com)
This is a very interesting concept, especially since RSV, a major cause of illness in very young children, has been difficult to both prevent and treat. Should the process described here pan out, it opens the door to the development of clinical applications.
Analysis of: FDA Approves Nexium for Use in Children Ages 1-11 Years (pharmalive.com)
As is the case with choice of PPI's in adult patients, in pediatrics we now have a large number of effective drugs from which to choose. However, "managed care" policies limit the choices and make the prescribing of newer products problematic.
Analysis of: Drug Pitchmen: Actor, Doctor or Pfizer’s Option (www.nytimes.com)
Why is the Jarvik ad campaign any more offensive than the famous line quoted above? If any direct-to-consumer (DTC) advertising is acceptable, then why is there any furor over the use of actors who are not technically qualified as pitchmen?
March 6, 2008
An Unhappy Trend
Analysis of: Your Hospital's Deadly Secret (www.portfolio.com)
As hospitals outsource everything, from laboratory management to emergency rooms to pharmacies, control of these areas is being lost, often to the detriment of patients.
Analysis of: Intercell completes Phase I clinical trial for improved seasonal Flu vaccine formulated with IC31(R) (www.pipelinereview.com)
While new adjuvants always hold promise, and Intercell's product seems to be efficacious without undue reactogenicity, any vaccine is only as good as its raw materials. This year's flu vaccine's lack of efficacy is a case in point.
Analysis of: As Healthcare Spending is Predicted to Exceed 4 Trillion in Less Than 10 Years, Technology will be Called upon to Stem the Tide (biz.yahoo.com)
New technology is one factor in the ever-increasing cost of healthcare.  New medical technologies  are seldom cost-saving.
Analysis of: Vaccinating Boys for Girls’ Sake? (www.nytimes.com)
While the disease incidence (cervical carcinoma) is lower than many other cancers, thanks in part to successful screening, many of the remaining cases could be prevented by vaccinating EVERY female prior to the onset of sexual activity. Since this universal coverage is not likely, vaccinating males...

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