September 25, 2008Why Not?
Analysis of:
Lilly to Disclose Payments to Doctors (online.wsj.com)
As physicians, we should have nothing to hide when we provide unbiased advice to pharmaceutical companies. Receiving a grant (or a lunch or a free pen) does not, for the vast majority, obligate us to be anything other than concerned for our patients, first and foremost.
Analysis of:
ACE Inhibitor May Ease Cardiac Risks in Marfan's Syndrome (www.medpagetoday.com)
In this small and short-duration study, ACE inhibitors seem to provide an additional preventive benefit when used with beta blockers in patients with marfan's syndrome. This is all to the good for those patients, and if the results of this preliminary study are borne out over a longer term, this may...
Analysis of:
Europe adopts new pediatric drug rule (www.nationalreviewofmedicine.com)
Children have long been therapeutic orphans, often relying on off-label use of new drugs which have only been tested on adults. This legislation seeks to remedy that inequality, by encouraging pharmaceutical companies to do more testing in pediatric populations.
Analysis of:
Abbott signs deal to promote Crestor in U.S. (www.chicagotribune.com)
With Abbott being such a major player in the infant formula market, will this lead to more promotion of statins in the pediatric office, especially given the recent (although controversial) recommendation for possible statin use in children as young as 8 years old? And since they are involved in the...
Analysis of:
Drug Makers’ Push Leads to Cancer Vaccines’ Fast Rise (www.nytimes.com)
Cervical cancer is real, and has the potential to cause significant morbidity and mortality. Yet the incidence in developed countries is relatively small, when compared with the developing world. There is a real, although small, benefit in the US, and while the vaccine is effective, the cost per prevented...
Analysis of:
Panel Urges End to Prostate Screening at Age 75 (www.nytimes.com)
Finally, a recommendation that an available test and treatment NOT be used, under circumstances where there is little to be gained and much to be lost.
Analysis of:
Majority of Patients Want Doc to use EHRs: Study (www.modernhealthcare.com)
Just like expensive, do-everything end-of-life care, like unlimited imaging studies, like newest drugs, patients want it all. This is one of the attitudes which causes the US to spend far more than other developed countries for far less efficient and cost-effective health care.
Analysis of:
Just Sitting Back to Get in Shape: Two Pills Do teh Work of Exercise (online.wsj.com)
(There ain't no such thing as a free lunch.) Just like the electronic devices which claim to stimulate constant muscle contractions, these pills seem to produce increased muscle metabolic activity, making the muscle "think" that it has been exercising. The animals in the study had increased endurance...
Analysis of:
Associations Between Exposure To Traffic-Related Air Pollution And The Onset Of Allergic Diseases In Children Shown By New Research (www.medicalnewstoday.com)
There is not much new here for those involved in clinical care of children, but it is good to have statistical support for what we have always taught about pollution and allergic disorders, especially asthma.
Analysis of:
Intermittent tacrolimus Ointment therapy Helps Prevent Relapse Of Stabilized Atpoic Dermatitis (www.medscape.com)
Treatment of atopic dermatitis has always been frustrating. Flare-ups, which are all too common, can be treated with topical steroids, but these cannot be used for prolonged periods without significant downside. And lubrication of the skin, the mainstay of maintenance therapy, is not always effective...
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