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GLG News by Multiple Myeloma Physicians

Analysis of: Cigarette Company Paid for Lung Cancer Study (www.nytimes.com)
Support from a cigarette manufacturer raises questions as to the conclusions from this study which says early detection by repetitive CT's can improve cancer cure rates by early detection. (making smoking safer?)
Analysis of: Prostate-Cancer Treatment Questioned (online.wsj.com)
Hormone blocking therapy is added to radiation, unnecessarily, in early prostate cancer patients. The result in early stage patients is unnecessary side effects and reduced quality of life. Go figure.
Analysis of: Vermillion Announces Positive Results From Clinical Trial of Ovarian Tumor Triage Test; Study Meets Primary Endpoints (www.pipelinereview.com)
Early detection of ovarian cancer is of paramount importance
Analysis of: Researchers Find Cause of Severe Allergic Reaction to Cancer Drug (pharmalive.com)
Antibodies have been identified that explain allergic reactions that can terminate it's use in individuals who "react."
Analysis of: Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab (content.nejm.org)
This exceedingly rare condition produces organ damage due to infiltration of blood eosinophils. Steroids are the only effective therapy in the non myeloproliferative subset of patients, so for the chosen few this drug will be invaluable.
Analysis of: MediGene Achieves Excellent Efficacy Data of EndoTAG (TM) 1 in Clinical Phase II Trial in Pancreatic Carcinoma (www.pipelinereview.com)
All major clinical trials in  patients with pancreatic cancer have generated questionable actual benefit
Analysis of: Piramed Announces Progress in its Collaboration with Genentech, Inc. (DNA) to Develop a New Class of Anti-cancer Drugs (www.pipelinereview.com)
The high cost of all the new agents is a major problem, especially in developing countries
Analysis of: Researchers Find Cause of Severe Allergic Reaction to Cancer Drug (pharmalive.com)
The role of immune system remains important and shouhd never neglected even with all these new molecules
Analysis of: Phase II Randomized Controlled Trial of an Epidermal Growth Factor Vaccine in Advanced Non–Small-Cell Lung Cancer (jco.ascopubs.org)
Vaccines have always been a hope but until now no significant results have been recorded in solid tumors
Analysis of: Phase II Randomized Controlled Trial of an Epidermal Growth Factor Vaccine in Advanced Non–Small-Cell Lung Cancer (jco.ascopubs.org)
Vaccination with EGF was used in a maintenance situation after initial chemo. No only did it produce EGF antibodies BUT the antibody response was correlated with survival!!

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