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January 18, 2008Major Win For Glaxo with Xenoport for Restless Legs syndrome -- Next Blockbuster?
Analysis of: GlaxoSmithKline and XenoPort report positive top-line results of second phase 3 restless legs syndrome trial for XP13512/GSK1838262 | www.pipelinereview.com
Author: Daniel Wynn, Director, Clinical Research, Consultants In Neurology Ltd.
Xenoport's trial for XP13512 in restless legs syndrome (RLS) shows strongly positive 9 month data in second phase 3 trial, should be a major win in the marketplace. RLS represent a major unmet need, for drugs with sustained efficacy and high tolerability.
August 30, 2007
Looking forward to Vical Phase 1 Trial of H5N1
Analysis of: Vical Begins Phase 1 Trial Of DNA Vaccine Against H5N1 Pandemic Influenza | www.medicalnewstoday.com
Author: GLG Expert Contributor
Analysis of: Vical Begins Phase 1 Trial Of DNA Vaccine Against H5N1 Pandemic Influenza | www.medicalnewstoday.com
Author: GLG Expert Contributor
I'm looking forward to the results of the H5N1 clincial trial. This might improve the world's chances of avoiding a pandemic like the one in 1918.
August 20, 2007
Vertebroplasty vs kyphoplasty vs arcuoplasty
Analysis of: Medtronic Buys Kyphon For $3.9 Billion | www.forbes.com
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
Vertebroplasty vs kyphoplasty vs arcuoplasty
Analysis of: Medtronic Buys Kyphon For $3.9 Billion | www.forbes.com
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
Will the recent purchase of Kyphon by Medtronic signals the end of kyphoplasty? No because arcuoplasty does not restore vertebral height. Vertebroplasty, kyphoplasty and arcuoplasty essentially achieve the same goals, which brings up the question, do we need all three techniques? Arcuoplasty is the...
July 11, 2007
Welcome addition
Analysis of: Shire Receives Approvable Letter from FDA for INTUNIV(TM) (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD | www.pipelinereview.com
Author: GLG Expert Contributor
Analysis of: Shire Receives Approvable Letter from FDA for INTUNIV(TM) (guanfacine) Extended Release, a Nonstimulant for the Treatment of ADHD | www.pipelinereview.com
Author: GLG Expert Contributor
This is a helpful agent in ADHD for hyperactive symptoms. A long-acting form is critical in ADHD so no doses need to interrupt the school day. More even blood levels also an advantage.
December 28, 2006
Glial Cells: The Nervous System is more than Neurons
Analysis of: New Insights into Neuron-Glia Communication | www.pubmedcentral.nih.gov
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
Glial Cells: The Nervous System is more than Neurons
Analysis of: New Insights into Neuron-Glia Communication | www.pubmedcentral.nih.gov
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
It has always been suspected that the supporting cells of the brain, called glial cells, have long held a secondary role behind neurons, the “telephone wires” of the brain. But, this role may have been grossly underestimated as new evidence suggests that glial cells may be able to sense and monitor...
December 21, 2006
RNA Interference (RNAi) Offers New Options in Medical Treatment
Analysis of: The Therapeutic Potential of RNAi | www.technologyreview.com
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
RNA Interference (RNAi) Offers New Options in Medical Treatment
Analysis of: The Therapeutic Potential of RNAi | www.technologyreview.com
Author: Luc Jasmin, Attending Neurosurgeon and a Research Scientist, Cedars-Sinai Medical Center
Post-translational gene silencing (PTGS) techniques, particularly the very popular RNA Interference (RNAi) technique, may be used to temporarily suppress the expression of particular genes in virtually all organisms. Where once believed to be limited to the plant species, the new discovery of its universal...
November 20, 2006
NC-Stat Technology
Analysis of: New Nerve Test, a Moneymaker, Divides Doctors | www.nytimes.com
Author: GLG Expert Contributor
Analysis of: New Nerve Test, a Moneymaker, Divides Doctors | www.nytimes.com
Author: GLG Expert Contributor
NC stat uses non needle surface EMG for the simple diagnosis of common disorders such as CTS. Unfortunatley, SEMG is not reliable. Its utility was questioned as far back as 2000 and the problems reaffirmed in a technology assessment at the AAN in 2003.
November 20, 2006
Poiorphi, natural pain killer
Analysis of: Natural chemical 'beats morphine' | news.bbc.co.uk
Author: GLG Expert Contributor
Analysis of: Natural chemical 'beats morphine' | news.bbc.co.uk
Author: GLG Expert Contributor
Revisiting endogenous opioids for pain control is rehasing old ground, which has been disappointing.
October 30, 2006
FDA approval for severe Alzheimer's disease
Analysis of: Aricept (donepezil) Wins Indication for Severe Alzheimer's | www.medpagetoday.com
Author: GLG Expert Contributor
Analysis of: Aricept (donepezil) Wins Indication for Severe Alzheimer's | www.medpagetoday.com
Author: GLG Expert Contributor
It is long waited decision. I have been using donepezil for last 4 to 5 years in moderate to severe Alzheimer's disease with good results. Only, I did not have statistical data.
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More GLG News in
Healthcare
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Source Article | Expert Analyses
Use of Antipsychotics in Children Is Criticized
www.nytimes.com
Personal medicine is goal of Eli Lilly & Co.
www.azcentral.com
Scientists recommend 'black box' for Avastin
www.fiercepharma.com
Are Costly Diabetes Pills Doing Any Good?
www.pharmalot.com
Use of Antipsychotics in Children Poses Risks of Adverse Effects
November 26, 2008
Avastin and clots? News to me. Black box warning? Why?
November 24, 2008
Off Label Use Can Be Prevented
November 24, 2008
Gardasil will most certainly be approved for boys
November 24, 2008
Medivations's (MDVN) Dimebon - We've Seen This Movie Before
November 24, 2008

